gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
638190490	360	53.15	1	359	1	365	0.0e+00	475	COG1163	Predicted GTPase	365
638190491	669	41.99	2	667	264	935	0.0e+00	727	COG3383	Uncharacterized anaerobic dehydrogenase	978
638190492	306	24.55	190	299	294	380	3.0e-07	49.5	COG1139	Uncharacterized conserved protein containing a ferredoxin-like domain	459
638190493	244	27.76	1	235	17	249	2.0e-39	156	COG0543	2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	252
638190494	476	17.69	50	458	60	446	1.0e-09	58.3	COG2271	Sugar phosphate permease	448
638190495	168	32.26	50	142	269	354	1.0e-12	66.3	COG0675	Transposase and inactivated derivatives	364
638190496	150	51.68	1	149	1	147	7.0e-55	206	COG2238	Ribosomal protein S19E (S16A)	147
638190497	115	57.39	3	115	2	116	3.0e-13	67.2	COG2118	DNA-binding protein	116
638190499	89	43.02	4	89	3	86	2.0e-18	83.8	COG2097	Ribosomal protein L31E	89
638190500	218	51.82	2	218	1	220	1.0e-73	269	COG1976	Translation initiation factor 6 (eIF-6)	222
638190501	166	42.69	1	164	5	175	4.0e-44	170	COG0461	Orotate phosphoribosyltransferase	201
638190502	627	25	14	621	13	642	1.0e-100	361	COG1199	Rad3-related DNA helicases	654
638190503	154	29.07	1	154	2	173	8.0e-19	86.2	COG0456	Acetyltransferases	177
638190504	400	65.51	2	400	1	400	0.0e+00	594	COG1812	Archaeal S-adenosylmethionine synthetase	400
638190505	489	48.15	1	489	3	515	0.0e+00	639	COG0138	AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	515
638190506	251	42.8	5	248	3	257	5.0e-55	208	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638190507	287	60	10	287	1	277	1.0e-82	299	COG3389	Uncharacterized protein conserved in archaea	277
638190508	770	34.96	6	582	2	569	0.0e+00	520	COG0550	Topoisomerase IA	570
638190508	770	31.93	654	769	1	115	8.0e-13	69.4	COG0551	Zn-finger domain associated with topoisomerase type I	140
638190509	90	48.35	1	90	2	92	2.0e-24	104	COG1254	Acylphosphatases	92
638190510	534	42.42	39	531	13	465	7.0e-70	258	COG3368	Predicted permease	465
638190511	259	39.22	1	252	1	255	1.0e-61	229	COG1131	ABC-type multidrug transport system, ATPase component	293
638190512	326	28.63	62	321	1	229	1.0e-33	137	COG1814	Uncharacterized membrane protein	229
638190513	449	50.89	3	446	1	444	0.0e+00	566	COG0160	4-aminobutyrate aminotransferase and related aminotransferases	447
638190515	258	26.78	2	257	4	294	6.0e-47	180	COG0003	Oxyanion-translocating ATPase	322
638190516	378	44.85	41	369	9	337	4.0e-86	311	COG0206	Cell division GTPase	338
638190517	219	29.44	1	212	10	240	1.0e-44	173	COG0284	Orotidine-5'-phosphate decarboxylase	240
638190518	230	37.13	2	230	60	296	2.0e-52	199	COG0616	Periplasmic serine proteases (ClpP class)	317
638190519	310	37.5	3	309	1	320	2.0e-85	309	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
638190520	481	46.61	14	478	1	486	0.0e+00	524	COG1492	Cobyric acid synthase	486
638190521	790	36.82	4	789	6	792	0.0e+00	872	COG0525	Valyl-tRNA synthetase	877
638190522	540	59.55	1	528	1	533	0.0e+00	806	COG0504	CTP synthase (UTP-ammonia lyase)	533
638190524	1088	46.09	833	1088	1	252	4.0e-115	410	COG1933	Archaeal DNA polymerase II, large subunit	253
638190525	257	21.99	5	185	8	193	4.0e-17	82	COG1100	GTPase SAR1 and related small G proteins	219
638190526	204	45.11	23	204	1	183	7.0e-52	197	COG1628	Uncharacterized conserved protein	185
638190528	170	62.07	1	170	1	171	9.0e-50	189	COG5592	Uncharacterized conserved protein	171
638190529	115	74.47	22	115	3	96	3.0e-34	137	COG3461	Uncharacterized conserved protein	103
638190530	197	38.79	1	163	3	167	3.0e-52	198	COG2150	Predicted regulator of amino acid metabolism, contains ACT domain	167
638190532	188	24.62	2	131	237	353	2.0e-15	75.9	COG0675	Transposase and inactivated derivatives	364
638190533	240	19.18	15	231	30	248	4.0e-11	61.9	COG3063	Tfp pilus assembly protein PilF	250
638190535	252	46.56	6	252	2	261	5.0e-80	290	COG0708	Exonuclease III	261
638190536	426	39.95	8	411	13	413	0.0e+00	480	COG0112	Glycine/serine hydroxymethyltransferase	413
638190538	185	35.94	1	185	2	193	1.0e-22	99	COG1390	Archaeal/vacuolar-type H+-ATPase subunit E	194
638190539	356	31.36	3	353	7	345	1.0e-73	270	COG1527	Archaeal/vacuolar-type H+-ATPase subunit C	346
638190540	104	33.01	2	103	2	104	8.0e-21	91.8	COG1436	Archaeal/vacuolar-type H+-ATPase subunit F	104
638190541	776	86.89	422	772	238	588	0.0e+00	604	COG1155	Archaeal/vacuolar-type H+-ATPase subunit A	588
638190542	460	69.38	1	454	2	455	0.0e+00	767	COG1156	Archaeal/vacuolar-type H+-ATPase subunit B	463
638190543	209	44.76	1	209	3	211	4.0e-45	174	COG1394	Archaeal/vacuolar-type H+-ATPase subunit D	211
638190545	643	33.38	2	637	1	660	0.0e+00	461	COG1269	Archaeal/vacuolar-type H+-ATPase subunit I	660
638190546	199	50	1	193	1	194	5.0e-70	257	COG0311	Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	194
638190547	359	41.85	1	359	6	371	1.0e-106	379	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
638190548	312	33.54	4	310	1	311	6.0e-53	201	COG0451	Nucleoside-diphosphate-sugar epimerases	314
638190550	205	34.85	8	199	8	204	2.0e-45	175	COG0605	Superoxide dismutase	204
638190551	204	55.71	1	204	1	210	9.0e-72	262	COG1059	Thermostable 8-oxoguanine DNA glycosylase	210
638190553	292	24.84	1	292	9	318	5.0e-38	151	COG0306	Phosphate/sulphate permeases	326
638190556	226	22.78	42	220	40	213	1.0e-09	57.2	COG1392	Phosphate transport regulator (distant homolog of PhoU)	217
638190557	212	41.43	1	210	1	203	1.0e-37	149	COG2095	Multiple antibiotic transporter	203
638190558	164	34.64	1	164	1	179	7.0e-37	146	COG1514	2'-5' RNA ligase	180
638190560	155	35.07	19	151	1	133	8.0e-31	126	COG1545	Predicted nucleic-acid-binding protein containing a Zn-ribbon	140
638190561	390	35.71	1	381	1	383	7.0e-83	301	COG0183	Acetyl-CoA acetyltransferase	392
638190562	435	18.08	2	425	1	392	2.0e-08	54.1	COG2814	Arabinose efflux permease	394
638190563	316	33.44	8	314	70	371	2.0e-70	259	COG0498	Threonine synthase	411
638190564	344	53.22	3	344	1	339	3.0e-128	452	COG3367	Uncharacterized conserved protein	339
638190566	333	33.51	5	333	1	358	3.0e-103	368	COG1312	D-mannonate dehydratase	362
638190567	261	41.54	4	246	3	251	6.0e-50	191	COG1028	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	251
638190568	164	49.4	1	164	11	176	3.0e-61	227	COG2042	Uncharacterized conserved protein	179
638190569	256	45.86	1	256	1	266	3.0e-87	314	COG1650	Uncharacterized protein conserved in archaea	266
638190570	335	23.89	1	335	2	356	7.0e-53	201	COG0079	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase	356
638190571	297	45.08	3	297	4	294	4.0e-23	102	COG1340	Uncharacterized archaeal coiled-coil protein	294
638190572	134	31.13	30	134	1	85	2.0e-08	51.7	COG2034	Predicted membrane protein	85
638190573	359	43.3	3	350	2	350	8.0e-86	310	COG1208	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)	358
638190575	455	32.03	1	452	1	453	3.0e-105	375	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
638190576	205	33.18	1	202	2	218	1.0e-50	192	COG0819	Putative transcription activator	218
638190579	201	19.23	6	131	4	124	2.0e-07	49.7	COG0596	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)	282
638190580	137	49.23	4	132	4	133	6.0e-41	159	COG0314	Molybdopterin converting factor, large subunit	149
638190582	284	48.67	22	244	50	262	3.0e-59	222	COG0489	ATPases involved in chromosome partitioning	265
638190583	536	62.32	1	536	11	554	0.0e+00	822	COG2759	Formyltetrahydrofolate synthetase	554
638190584	204	60.29	1	204	5	208	1.0e-65	242	COG3404	Methenyl tetrahydrofolate cyclohydrolase	208
638190585	302	65.35	1	302	2	302	0.0e+00	483	COG3643	Glutamate formiminotransferase	302
638190586	769	35.29	10	728	1	689	0.0e+00	571	COG0209	Ribonucleotide reductase, alpha subunit	696
638190587	260	27.99	10	247	2	269	4.0e-36	145	COG1235	Metal-dependent hydrolases of the beta-lactamase superfamily I	269
638190588	592	34.15	15	461	2	443	1.0e-84	308	COG0038	Chloride channel protein EriC	443
638190588	592	26.06	448	580	131	272	1.0e-05	45.3	COG2905	Predicted signal-transduction protein containing cAMP-binding and CBS domains	610
638190590	212	40.53	1	212	2	228	3.0e-65	241	COG2045	Phosphosulfolactate phosphohydrolase and related enzymes	230
638190592	193	44.15	4	190	2	184	7.0e-60	223	COG2096	Uncharacterized conserved protein	184
638190593	436	43.24	1	424	4	454	3.0e-121	428	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	454
638190594	400	42.93	2	399	3	404	2.0e-105	376	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	404
638190595	319	64.71	1	318	2	324	0.0e+00	500	COG0022	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	324
638190596	337	46.85	10	336	26	358	4.0e-112	398	COG1071	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	358
638190597	291	35.43	1	291	6	252	7.0e-60	224	COG0024	Methionine aminopeptidase	255
638190599	86	43.82	1	86	1	89	3.0e-19	86.8	COG1343	Uncharacterized protein predicted to be involved in DNA repair	89
638190600	322	35.19	1	319	4	325	3.0e-79	288	COG1518	Uncharacterized protein predicted to be involved in DNA repair	327
638190602	385	31.28	1	385	1	367	1.0e-79	290	COG1332	Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)	369
638190603	296	32.88	7	296	19	308	5.0e-70	257	COG1567	Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)	313
638190604	229	39.09	2	229	1	235	3.0e-46	178	COG1337	Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)	249
638190605	160	33.33	25	158	1	137	1.0e-27	116	COG1421	Uncharacterized protein predicted to be involved in DNA repair	137
638190606	775	30.26	1	775	1	797	0.0e+00	467	COG1353	Predicted hydrolase of the HD superfamily (permuted catalytic motifs)	799
638190607	237	33.2	1	236	1	240	5.0e-44	171	COG1583	Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)	240
638190608	406	31.6	1	406	1	405	3.0e-73	269	COG1517	Uncharacterized protein predicted to be involved in DNA repair	406
638190611	248	39.59	6	248	1	244	1.0e-69	256	COG1938	Archaeal enzymes of ATP-grasp superfamily	244
638190612	64	35.29	1	64	2	68	2.0e-07	47.1	COG2104	Sulfur transfer protein involved in thiamine biosynthesis	68
638190613	437	46.85	1	432	4	443	0.0e+00	511	COG1746	tRNA nucleotidyltransferase (CCA-adding enzyme)	443
638190614	119	50.82	1	118	1	122	5.0e-28	116	COG1308	Transcription factor homologous to NACalpha-BTF3	122
638190616	145	27.16	65	145	51	116	3.0e-06	44.6	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
638190617	163	43.86	1	163	7	177	4.0e-49	187	COG1439	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module	177
638190618	129	33.59	1	127	11	137	3.0e-26	110	COG3439	Uncharacterized conserved protein	137
638190619	531	36.61	6	507	10	522	0.0e+00	470	COG0365	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases	528
638190620	471	18.29	22	448	12	397	5.0e-08	52.9	COG2223	Nitrate/nitrite transporter	417
638190624	688	13.32	37	675	1	590	1.0e-49	191	COG2189	Adenine specific DNA methylase Mod	590
638190626	502	26.5	3	494	2	524	8.0e-48	185	COG0318	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II	534
638190627	480	41.36	21	197	5	195	3.0e-46	179	COG0062	Uncharacterized conserved protein	203
638190627	480	39.65	205	478	1	284	4.0e-72	265	COG0063	Predicted sugar kinase	284
638190628	339	40.06	1	321	1	314	1.0e-79	289	COG0667	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)	316
638190630	351	59.15	1	351	2	355	3.0e-120	425	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
638190631	387	38.25	2	386	1	390	8.0e-80	291	COG0183	Acetyl-CoA acetyltransferase	392
638190632	135	47.01	1	133	8	139	7.0e-36	142	COG1545	Predicted nucleic-acid-binding protein containing a Zn-ribbon	140
638190633	218	30.84	11	218	1	199	2.0e-46	178	COG0164	Ribonuclease HII	199
638190637	306	50.98	205	306	121	215	1.0e-28	120	COG1072	Panthothenate kinase	283
638190638	396	20	28	383	30	384	4.0e-15	76.4	COG2814	Arabinose efflux permease	394
638190641	52	48.94	1	47	6	52	6.0e-13	65.7	COG3466	Putative transposon-encoded protein	52
638190642	267	40.45	1	267	1	259	2.0e-100	358	COG5558	Transposase	261
638190646	482	26.99	3	471	1	486	2.0e-51	197	COG0591	Na+/proline symporter	493
638190648	1344	41.24	765	1344	3	589	8.0e-124	439	COG4934	Predicted protease	1174
638190649	239	40.17	1	230	2	240	7.0e-60	223	COG1131	ABC-type multidrug transport system, ATPase component	293
638190652	338	29.26	1	336	5	347	7.0e-72	264	COG2038	NaMN:DMB phosphoribosyltransferase	347
638190653	340	37.12	83	339	6	265	1.0e-64	240	COG0294	Dihydropteroate synthase and related enzymes	274
638190654	426	36.26	1	422	2	426	6.0e-109	388	COG0124	Histidyl-tRNA synthetase	429
638190655	495	37.79	11	485	12	432	7.0e-113	401	COG1067	Predicted ATP-dependent protease	647
638190656	444	24.11	21	442	34	563	3.0e-44	173	COG0358	DNA primase (bacterial type)	568
638190657	341	26.27	1	328	1	280	3.0e-54	205	COG0648	Endonuclease IV	280
638190658	96	61.46	1	96	1	96	5.0e-32	128	COG4004	Uncharacterized protein conserved in archaea	96
638190659	204	74.39	39	202	1	161	1.0e-52	199	COG5615	Predicted integral membrane protein	161
638190660	90	35.63	1	87	1	87	3.0e-15	73.6	COG0776	Bacterial nucleoid DNA-binding protein	94
638190661	459	22.78	35	459	1	427	4.0e-92	332	COG5421	Transposase	480
638190662	184	45.45	31	184	4	148	3.0e-42	164	COG0049	Ribosomal protein S7	148
638190663	142	40.58	5	142	1	124	9.0e-35	139	COG0048	Ribosomal protein S12	129
638190664	338	41.16	1	333	3	345	4.0e-102	364	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
638190665	305	39.23	1	256	2	261	8.0e-60	224	COG1131	ABC-type multidrug transport system, ATPase component	293
638190667	202	21.74	1	202	10	216	1.0e-20	93	COG0491	Zn-dependent hydrolases, including glyoxylases	252
638190668	398	33.51	1	377	2	372	3.0e-80	292	COG4948	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	372
638190669	238	21.74	10	238	1	249	8.0e-27	114	COG0467	RecA-superfamily ATPases implicated in signal transduction	260
638190670	69	53.62	1	69	10	78	4.0e-23	99.7	COG3369	Uncharacterized conserved protein	78
638190671	200	45.85	2	200	1	200	1.0e-64	238	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
638190673	190	33.49	1	190	4	207	5.0e-35	140	COG0125	Thymidylate kinase	208
638190674	394	41.67	8	392	1	396	0.0e+00	463	COG0626	Cystathionine beta-lyases/cystathionine gamma-synthases	396
638190675	249	36	1	248	1	228	5.0e-63	234	COG0274	Deoxyribose-phosphate aldolase	228
638190676	470	19.86	1	408	5	396	5.0e-14	72.9	COG2271	Sugar phosphate permease	448
638190678	172	46.29	1	172	5	178	7.0e-48	183	COG1779	C4-type Zn-finger protein	201
638190679	347	31.59	2	347	10	360	4.0e-76	278	COG1304	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	360
638190680	244	46.18	2	244	3	251	4.0e-79	287	COG1608	Predicted archaeal kinase	252
638190681	176	27.37	6	176	2	180	6.0e-18	83.9	COG1670	Acetyltransferases, including N-acetylases of ribosomal proteins	187
638190682	263	17.55	14	244	1	214	1.0e-11	63.7	COG0491	Zn-dependent hydrolases, including glyoxylases	252
638190683	321	29.09	5	218	2	210	1.0e-30	127	COG0704	Phosphate uptake regulator	240
638190685	196	50	3	196	1	187	6.0e-67	246	COG3620	Predicted transcriptional regulator with C-terminal CBS domains	187
638190686	183	23.79	5	183	30	235	1.0e-06	46.5	COG0575	CDP-diglyceride synthetase	265
638190687	117	51.26	1	117	4	122	2.0e-37	147	COG1990	Uncharacterized conserved protein	122
638190689	881	58.92	1	879	1	861	0.0e+00	1221	COG1048	Aconitase A	861
638190690	406	51.3	1	343	1	347	5.0e-117	414	COG1171	Threonine dehydratase	347
638190691	183	27.67	1	183	75	278	5.0e-31	127	COG2890	Methylase of polypeptide chain release factors	280
638190693	192	25.42	3	159	11	178	8.0e-12	63.8	COG2226	Methylase involved in ubiquinone/menaquinone biosynthesis	238
638190694	230	30.34	20	229	1	231	7.0e-38	150	COG0710	3-dehydroquinate dehydratase	231
638190695	405	60.69	1	401	3	407	0.0e+00	591	COG0538	Isocitrate dehydrogenases	407
638190696	235	43.19	3	213	1	210	6.0e-68	250	COG1859	RNA:NAD 2'-phosphotransferase	211
638190697	286	34.67	1	284	5	303	2.0e-71	262	COG0462	Phosphoribosylpyrophosphate synthetase	314
638190698	243	40.82	1	239	5	248	8.0e-51	193	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638190699	333	38.76	1	306	6	301	8.0e-83	300	COG2971	Predicted N-acetylglucosamine kinase	301
638190700	589	54.62	1	589	8	608	0.0e+00	867	COG1274	Phosphoenolpyruvate carboxykinase (GTP)	608
638190701	242	45.64	2	242	2	238	4.0e-72	264	COG2872	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	241
638190702	254	25.4	47	232	6	179	3.0e-18	85.4	COG3634	Alkyl hydroperoxide reductase, large subunit	520
638190704	519	22.22	15	470	1	429	2.0e-31	130	COG1653	ABC-type sugar transport system, periplasmic component	433
638190705	296	35.17	7	294	3	288	5.0e-40	158	COG1175	ABC-type sugar transport systems, permease components	295
638190706	268	35.19	3	265	9	278	2.0e-40	159	COG0395	ABC-type sugar transport system, permease component	281
638190707	353	47.38	4	347	1	338	3.0e-113	401	COG3839	ABC-type sugar transport systems, ATPase components	338
638190709	1013	26.37	1	1010	1	943	0.0e+00	599	COG0383	Alpha-mannosidase	943
638190710	122	40.91	7	116	8	117	5.0e-22	96.6	COG1733	Predicted transcriptional regulators	120
638190711	177	44.83	1	172	19	192	7.0e-48	183	COG2353	Uncharacterized conserved protein	192
638190712	304	34.56	2	296	3	276	2.0e-68	252	COG1741	Pirin-related protein	276
638190713	352	38.46	4	243	1	247	2.0e-48	186	COG1378	Predicted transcriptional regulators	247
638190714	121	30.77	15	117	18	121	1.0e-15	75.2	COG1917	Uncharacterized conserved protein, contains double-stranded beta-helix domain	131
638190715	201	40.2	9	197	64	267	1.0e-54	206	COG2041	Sulfite oxidase and related enzymes	271
638190717	619	30.03	190	532	1	372	5.0e-54	206	COG0366	Glycosidases	505
638190721	533	23.41	21	456	5	439	4.0e-27	116	COG0531	Amino acid transporters	466
638190724	251	18.34	1	160	14	159	4.0e-07	48.8	COG0681	Signal peptidase I	166
638190725	174	52.75	1	174	2	183	1.0e-62	232	COG0450	Peroxiredoxin	194
638190726	226	23.11	8	221	4	228	1.0e-14	73.6	COG0463	Glycosyltransferases involved in cell wall biogenesis	291
638190728	138	45.76	20	135	7	124	6.0e-30	123	COG2450	Uncharacterized conserved protein	124
638190730	895	28.84	2	895	2	908	4.0e-87	316	COG0419	ATPase involved in DNA repair	908
638190731	374	26.77	2	374	1	388	2.0e-52	200	COG0420	DNA repair exonuclease	390
638190732	511	31.47	1	479	4	514	1.0e-53	204	COG0433	Predicted ATPase	520
638190733	335	28.69	1	335	17	359	2.0e-46	180	COG1630	Uncharacterized protein conserved in archaea	379
638190734	287	36.71	3	284	1	285	5.0e-74	271	COG2084	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	286
638190735	547	41.53	9	345	11	363	2.0e-100	360	COG1902	NADH:flavin oxidoreductases, Old Yellow Enzyme family	363
638190740	232	27.48	1	221	5	214	8.0e-37	147	COG3413	Predicted DNA binding protein	215
638190743	386	41.49	1	385	9	390	9.0e-117	413	COG0372	Citrate synthase	390
638190744	105	37.61	1	105	4	112	9.0e-27	111	COG1416	Uncharacterized conserved protein	112
638190746	981	69.35	14	980	13	978	0.0e+00	1626	COG3383	Uncharacterized anaerobic dehydrogenase	978
638190747	104	43.43	6	104	50	148	2.0e-13	67.3	COG2427	Uncharacterized conserved protein	148
638190748	279	42.38	11	278	6	265	2.0e-79	289	COG1526	Uncharacterized protein required for formate dehydrogenase activity	266
638190749	416	14.44	44	415	53	388	2.0e-07	50.6	COG2814	Arabinose efflux permease	394
638190750	252	28.3	28	128	41	146	1.0e-12	66.8	COG2226	Methylase involved in ubiquinone/menaquinone biosynthesis	238
638190752	386	22.26	34	360	43	354	1.0e-20	94.4	COG0675	Transposase and inactivated derivatives	364
638190753	158	40.15	19	152	2	138	2.0e-33	135	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	138
638190754	380	20.76	18	366	42	433	9.0e-12	64.8	COG2271	Sugar phosphate permease	448
638190755	471	31.15	3	455	2	453	2.0e-102	366	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	454
638190756	74	45.76	1	58	1	59	2.0e-08	50.4	COG2608	Copper chaperone	71
638190759	359	20	87	320	131	373	6.0e-11	62.1	COG0750	Predicted membrane-associated Zn-dependent proteases 1	375
638190762	201	32.29	1	181	2	192	5.0e-31	127	COG0406	Fructose-2,6-bisphosphatase	208
638190764	423	25.4	27	422	6	442	3.0e-56	212	COG1524	Uncharacterized proteins of the AP superfamily	450
638190765	305	54.02	3	305	2	312	5.0e-117	414	COG0549	Carbamate kinase	312
638190766	224	44.28	11	209	1	192	1.0e-45	176	COG2236	Predicted phosphoribosyltransferases	192
638190767	109	25.58	12	96	15	97	5.0e-07	46.1	COG0494	NTP pyrophosphohydrolases including oxidative damage repair enzymes	161
638190769	354	30.48	8	354	3	322	1.0e-60	226	COG0142	Geranylgeranyl pyrophosphate synthase	322
638190770	283	33.22	1	282	1	299	6.0e-56	211	COG4974	Site-specific recombinase XerD	300
638190771	211	45.07	1	211	4	213	5.0e-68	250	COG0036	Pentose-5-phosphate-3-epimerase	220
638190772	328	31.38	1	327	4	339	7.0e-55	208	COG1064	Zn-dependent alcohol dehydrogenases	339
638190774	49	68.09	3	49	4	50	5.0e-07	46.1	COG1552	Ribosomal protein L40E	50
638190775	258	41.67	3	254	1	231	8.0e-75	273	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
638190776	415	34.03	1	401	1	429	8.0e-88	317	COG0044	Dihydroorotase and related cyclic amidohydrolases	430
638190777	197	43.94	4	196	1	198	3.0e-68	250	COG2263	Predicted RNA methylase	198
638190779	305	55.7	1	304	4	310	4.0e-124	438	COG0078	Ornithine carbamoyltransferase	310
638190780	285	55.75	1	285	2	287	6.0e-106	377	COG0074	Succinyl-CoA synthetase, alpha subunit	293
638190781	384	45.43	20	383	1	383	2.0e-123	436	COG0045	Succinyl-CoA synthetase, beta subunit	387
638190782	409	38.05	4	409	2	403	4.0e-93	335	COG1517	Uncharacterized protein predicted to be involved in DNA repair	406
638190786	179	25.87	1	178	4	201	1.0e-20	92.7	COG0237	Dephospho-CoA kinase	201
638190789	98	48.98	10	98	1	98	2.0e-19	87.3	COG2023	RNase P subunit RPR2	105
638190790	224	24.52	2	224	3	263	9.0e-32	130	COG0561	Predicted hydrolases of the HAD superfamily	264
638190791	277	55.51	7	277	1	270	8.0e-104	369	COG2107	Predicted periplasmic solute-binding protein	272
638190793	354	36.5	21	352	10	334	6.0e-49	188	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638190794	324	25.24	4	303	1	314	1.0e-27	117	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638190795	431	36.71	7	426	4	424	7.0e-78	284	COG1055	Na+/H+ antiporter NhaD and related arsenite permeases	424
638190796	157	41.4	1	157	2	156	5.0e-48	183	COG1225	Peroxiredoxin	157
638190797	436	46.4	10	435	1	426	0.0e+00	553	COG0104	Adenylosuccinate synthase	430
638190798	122	53.12	1	122	2	129	2.0e-39	154	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
638190799	197	38.5	1	197	8	204	6.0e-59	220	COG0293	23S rRNA methylase	205
638190801	326	44.87	17	326	1	311	3.0e-91	328	COG1395	Predicted transcriptional regulator	313
638190802	151	34.51	4	142	4	145	9.0e-32	129	COG0735	Fe2+/Zn2+ uptake regulation proteins	145
638190803	310	56.19	1	310	2	315	0.0e+00	469	COG0519	GMP synthase, PP-ATPase domain/subunit	315
638190805	77	31.58	3	76	69	144	5.0e-07	45.8	COG1522	Transcriptional regulators	154
638190806	209	35.51	3	205	6	212	2.0e-41	162	COG0602	Organic radical activating enzymes	212
638190807	434	40.63	2	434	17	448	0.0e+00	522	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
638190808	472	53.22	5	472	1	481	0.0e+00	710	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
638190809	336	31.35	12	310	5	322	1.0e-41	164	COG0535	Predicted Fe-S oxidoreductases	347
638190812	276	41.2	1	273	2	285	1.0e-94	339	COG1831	Predicted metal-dependent hydrolase (urease superfamily)	285
638190813	404	46.57	13	404	1	402	3.0e-130	458	COG1602	Uncharacterized conserved protein	402
638190814	465	19.23	10	162	8	163	1.0e-07	51.4	COG2814	Arabinose efflux permease	394
638190815	242	49.78	15	242	1	229	4.0e-59	221	COG0638	20S proteasome, alpha and beta subunits	236
638190816	230	58.44	1	230	1	231	5.0e-79	287	COG1500	Predicted exosome subunit	234
638190817	236	50.21	2	231	2	239	2.0e-74	272	COG1097	RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)	239
638190818	248	46.09	10	236	1	230	1.0e-73	269	COG0689	RNase PH	230
638190819	260	55.6	3	260	1	268	1.0e-89	322	COG2123	RNase PH-related exoribonuclease	272
638190820	80	51.95	4	80	3	79	5.0e-22	96.2	COG1997	Ribosomal protein L37AE/L43A	89
638190821	45	56.52	1	45	4	49	7.0e-06	42.3	COG1996	DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger)	49
638190822	388	48.59	3	388	7	394	0.0e+00	484	COG1258	Predicted pseudouridylate synthase	398
638190823	98	52.08	3	98	1	96	2.0e-30	123	COG2139	Ribosomal protein L21E	98
638190824	103	41.51	1	103	8	113	6.0e-23	99.2	COG1460	Uncharacterized protein conserved in archaea	114
638190825	182	66.3	1	182	15	196	1.0e-68	252	COG1491	Predicted RNA-binding protein	202
638190826	237	33.07	1	236	2	258	2.0e-53	202	COG0030	Dimethyladenosine transferase (rRNA methylation)	259
638190827	274	39.81	4	207	2	212	3.0e-33	135	COG0330	Membrane protease subunits, stomatin/prohibitin homologs	291
638190830	164	39.13	73	164	1	90	2.0e-18	85.3	COG3432	Predicted transcriptional regulator	95
638190832	72	70.18	18	72	1	57	1.0e-15	74.6	COG4023	Preprotein translocase subunit Sec61beta	57
638190833	320	29.09	1	320	1	328	8.0e-80	290	COG3407	Mevalonate pyrophosphate decarboxylase	329
638190834	272	29.71	92	265	29	203	1.0e-25	110	COG0586	Uncharacterized membrane-associated protein	208
638190836	525	14.55	17	229	2	207	1.0e-11	65.2	COG0750	Predicted membrane-associated Zn-dependent proteases 1	375
638190838	135	27.52	2	109	253	354	3.0e-12	64.7	COG0675	Transposase and inactivated derivatives	364
638190839	331	29.54	39	316	1	218	2.0e-48	186	COG0087	Ribosomal protein L3	218
638190840	255	32.38	2	243	1	214	2.0e-40	159	COG0088	Ribosomal protein L4	214
638190841	83	45.98	1	83	1	87	1.0e-14	71.4	COG0089	Ribosomal protein L23	94
638190842	234	43.04	1	228	34	265	4.0e-66	244	COG0090	Ribosomal protein L2	275
638190843	151	41.49	56	144	1	93	4.0e-24	104	COG0185	Ribosomal protein S19	93
638190844	148	31.94	4	145	1	117	1.0e-23	102	COG0091	Ribosomal protein L22	120
638190845	225	34.82	2	218	8	228	3.0e-55	208	COG0092	Ribosomal protein S3	233
638190847	100	53.12	1	96	4	98	2.0e-20	90.3	COG0023	Translation initiation factor 1 (eIF-1/SUI1) and related proteins	104
638190848	89	47.13	1	83	9	95	1.0e-23	101	COG1588	RNase P/RNase MRP subunit p29	95
638190849	109	51.76	25	109	1	84	3.0e-22	96.8	COG0186	Ribosomal protein S17	87
638190850	132	46.03	11	132	1	122	6.0e-33	132	COG0093	Ribosomal protein L14	122
638190851	145	26.6	20	101	1	92	9.0e-07	46.4	COG0198	Ribosomal protein L24	104
638190852	235	47.9	1	232	4	241	4.0e-82	297	COG1471	Ribosomal protein S4E	241
638190853	170	45.62	1	150	23	180	4.0e-43	167	COG0094	Ribosomal protein L5	180
638190854	53	46	7	53	13	60	3.0e-06	43.7	COG0199	Ribosomal protein S14	61
638190855	129	46.97	1	129	2	132	2.0e-34	137	COG0096	Ribosomal protein S8	132
638190856	178	31.76	10	177	9	173	5.0e-35	140	COG0097	Ribosomal protein L6P/L9E	178
638190857	128	61.42	2	128	1	127	2.0e-40	158	COG1717	Ribosomal protein L32E	133
638190858	149	56.85	4	149	5	150	6.0e-37	146	COG2147	Ribosomal protein L19E	150
638190859	160	33.33	1	122	5	125	2.0e-24	105	COG0256	Ribosomal protein L18	125
638190860	221	36.82	16	216	1	181	2.0e-45	175	COG0098	Ribosomal protein S5	181
638190861	165	43.64	2	56	1	55	1.0e-13	69.4	COG1841	Ribosomal protein L30/L7E	55
638190862	145	25.97	1	141	1	152	5.0e-16	77.2	COG0200	Ribosomal protein L15	152
638190863	565	27.29	48	564	1	436	2.0e-69	257	COG0201	Preprotein translocase subunit SecY	436
638190864	181	57.38	1	181	5	187	2.0e-65	241	COG2019	Archaeal adenylate kinase	189
638190865	225	36.95	15	213	1	201	4.0e-50	191	COG1422	Predicted membrane protein	201
638190866	190	50	1	182	1	179	1.0e-61	229	COG1102	Cytidylate kinase	179
638190867	353	39.23	5	261	11	256	2.0e-66	246	COG0130	Pseudouridine synthase	271
638190868	259	40.43	76	259	168	355	3.0e-54	205	COG1498	Protein implicated in ribosomal biogenesis, Nop56p homolog	395
638190869	474	53.12	16	473	1	465	0.0e+00	638	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
638190870	54	56.36	1	54	1	54	7.0e-09	52.3	COG2126	Ribosomal protein L37E	61
638190871	87	36.71	7	81	1	79	3.0e-12	63.4	COG1958	Small nuclear ribonucleoprotein (snRNP) homolog	79
638190872	277	20	2	259	2	306	7.0e-12	64.6	COG0451	Nucleoside-diphosphate-sugar epimerases	314
638190874	299	32.66	1	299	9	355	6.0e-72	264	COG3276	Selenocysteine-specific translation elongation factor	447
638190877	649	29.49	348	634	96	386	3.0e-47	183	COG0348	Polyferredoxin	386
638190878	228	27.54	10	222	1	236	1.0e-23	103	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638190879	209	29.77	3	206	1	213	4.0e-31	128	COG3413	Predicted DNA binding protein	215
638190880	172	31.03	1	166	18	191	9.0e-35	139	COG2353	Uncharacterized conserved protein	192
638190881	265	27.73	20	239	1	176	9.0e-23	101	COG0723	Rieske Fe-S protein	177
638190882	537	29.6	22	392	25	372	2.0e-59	223	COG1290	Cytochrome b subunit of the bc complex	381
638190883	272	53.9	1	269	21	289	3.0e-94	338	COG2513	PEP phosphonomutase and related enzymes	289
638190884	443	32.16	1	440	3	453	0.0e+00	465	COG2079	Uncharacterized protein involved in propionate catabolism	453
638190885	272	33.2	9	264	10	246	3.0e-44	171	COG0805	Sec-independent protein secretion pathway component TatC	255
638190886	104	27.37	8	102	5	94	3.0e-11	60.4	COG1826	Sec-independent protein secretion pathway components	94
638190887	279	28.5	25	228	1	177	1.0e-26	114	COG0723	Rieske Fe-S protein	177
638190888	391	29.46	3	379	2	367	7.0e-57	214	COG1290	Cytochrome b subunit of the bc complex	381
638190892	175	22.36	3	162	1	149	7.0e-12	63.9	COG1522	Transcriptional regulators	154
638190894	632	14.77	39	625	11	520	5.0e-16	80	COG0433	Predicted ATPase	520
638190897	375	35.79	1	367	123	494	2.0e-72	266	COG0464	ATPases of the AAA+ class	494
638190900	328	29.55	2	328	2	331	6.0e-77	281	COG0460	Homoserine dehydrogenase	333
638190901	270	45.42	19	269	2	248	7.0e-82	297	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
638190902	541	62.36	1	534	1	523	0.0e+00	655	COG4986	ABC-type anion transport system, duplicated permease component	523
638190903	174	24.39	16	174	63	226	1.0e-10	60	COG1814	Uncharacterized membrane protein	229
638190904	95	54.74	1	95	3	97	7.0e-28	115	COG1888	Uncharacterized protein conserved in archaea	97
638190905	321	25.84	1	318	4	330	1.0e-45	176	COG0673	Predicted dehydrogenases and related proteins	342
638190907	156	64.74	1	156	1	156	2.0e-60	225	COG4754	Uncharacterized conserved protein	157
638190908	393	27.23	1	380	3	378	9.0e-33	134	COG0475	Kef-type K+ transport systems, membrane components	397
638190911	139	29.1	22	139	1	134	3.0e-21	94.7	COG3255	Putative sterol carrier protein	134
638190912	373	37.96	1	373	2	377	1.0e-103	370	COG1454	Alcohol dehydrogenase, class IV	377
638190913	498	39.87	7	481	1	470	0.0e+00	475	COG1012	NAD-dependent aldehyde dehydrogenases	472
638190914	396	50.39	4	390	1	388	0.0e+00	476	COG0156	7-keto-8-aminopelargonate synthetase and related enzymes	388
638190915	206	36.32	14	187	4	225	1.0e-48	186	COG0052	Ribosomal protein S2	252
638190916	292	29.41	108	289	1	181	5.0e-31	128	COG1676	tRNA splicing endonuclease	181
638190917	171	20.74	8	133	6	140	3.0e-10	58.1	COG1100	GTPase SAR1 and related small G proteins	219
638190918	402	42.96	5	400	67	459	8.0e-117	414	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	459
638190919	328	36.93	151	323	2	175	3.0e-55	208	COG1986	Uncharacterized conserved protein	175
638190919	328	54.97	1	150	6	156	5.0e-56	211	COG1019	Predicted nucleotidyltransferase	158
638190920	271	22.38	1	270	19	304	2.0e-25	109	COG0530	Ca2+/Na+ antiporter	320
638190921	130	41.73	1	127	10	136	6.0e-43	166	COG1586	S-adenosylmethionine decarboxylase	136
638190922	264	42.41	13	262	5	260	6.0e-87	314	COG1497	Predicted transcriptional regulator	260
638190923	290	34.49	2	284	5	288	1.0e-34	140	COG0382	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases	289
638190924	481	47.31	1	481	1	477	0.0e+00	586	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases	477
638190925	454	48.78	4	444	1	450	0.0e+00	579	COG1797	Cobyrinic acid a,c-diamide synthase	451
638190926	251	54.05	1	251	1	258	2.0e-96	345	COG2047	Uncharacterized protein (ATP-grasp superfamily)	258
638190927	62	55.93	1	59	1	59	2.0e-15	74.3	COG2260	Predicted Zn-ribbon RNA-binding protein	59
638190928	254	50.38	1	254	3	262	9.0e-84	303	COG1093	Translation initiation factor 2, alpha subunit (eIF-2alpha)	269
638190929	65	53.85	1	65	2	66	2.0e-18	84.2	COG2051	Ribosomal protein S27E	67
638190930	93	64.89	1	93	1	94	2.0e-25	106	COG1631	Ribosomal protein L44E	94
638190931	115	61.05	21	115	1	95	2.0e-34	137	COG3377	Uncharacterized conserved protein	95
638190933	273	44.68	3	273	1	281	5.0e-85	307	COG0421	Spermidine synthase	282
638190934	310	51.79	7	310	7	312	7.0e-116	410	COG1899	Deoxyhypusine synthase	318
638190935	154	54.84	3	149	1	155	6.0e-56	209	COG1225	Peroxiredoxin	157
638190936	104	49.54	1	104	1	109	4.0e-14	70	COG2058	Ribosomal protein L12E/L44/L45/RPP1/RPP2	109
638190937	314	29.9	3	195	3	175	9.0e-23	101	COG0244	Ribosomal protein L10	175
638190938	217	39.63	1	211	18	225	1.0e-48	186	COG0081	Ribosomal protein L1	228
638190939	158	46.43	1	140	4	141	4.0e-38	150	COG0080	Ribosomal protein L11	141
638190940	187	35.18	2	187	2	188	2.0e-29	122	COG0693	Putative intracellular protease/amidase	188
638190942	372	31.42	40	361	4	329	4.0e-83	301	COG3407	Mevalonate pyrophosphate decarboxylase	329
638190945	659	37.44	31	659	4	612	0.0e+00	523	COG3387	Glucoamylase and related glycosyl hydrolases	612
638190946	601	35.74	2	598	2	612	0.0e+00	490	COG3408	Glycogen debranching enzyme	641
638190947	369	20.57	2	369	1	377	3.0e-31	129	COG0438	Glycosyltransferase	381
638190948	378	35.38	1	378	85	508	2.0e-85	310	COG1449	Alpha-amylase/alpha-mannosidase	615
638190949	274	42.18	1	270	2	294	5.0e-75	274	COG1446	Asparaginase	307
638190952	314	28.84	1	308	2	306	5.0e-44	171	COG1208	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)	358
638190953	469	20.21	81	459	53	392	5.0e-11	62.5	COG2814	Arabinose efflux permease	394
638190954	407	42.06	1	407	1	427	7.0e-108	384	COG1236	Predicted exonuclease of the beta-lactamase fold involved in RNA processing	427
638190955	257	47.58	1	240	16	262	2.0e-81	295	COG0005	Purine nucleoside phosphorylase	262
638190956	236	25.69	1	228	208	460	4.0e-29	121	COG0367	Asparagine synthase (glutamine-hydrolyzing)	542
638190957	593	62.17	2	593	6	604	0.0e+00	832	COG1855	ATPase (PilT family)	604
638190958	170	61.49	1	170	1	174	5.0e-64	236	COG4344	Uncharacterized protein conserved in archaea	175
638190959	347	18.03	40	341	8	292	2.0e-20	93.5	COG0863	DNA modification methylase	302
638190960	226	38.27	5	191	3	193	1.0e-42	166	COG0450	Peroxiredoxin	194
638190962	312	33.45	28	299	1	263	3.0e-48	185	COG0037	Predicted ATPase of the PP-loop superfamily implicated in cell cycle control	298
638190963	390	27.6	162	379	1	210	5.0e-38	152	COG3413	Predicted DNA binding protein	215
638190964	367	29.03	160	362	7	250	1.0e-31	131	COG1028	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	251
638190964	367	32.55	1	198	1	209	2.0e-37	150	COG1063	Threonine dehydrogenase and related Zn-dependent dehydrogenases	350
638190966	121	55.56	4	120	1	116	2.0e-22	98.1	COG1358	Ribosomal protein HS6-type (S12/L30/L7a)	116
638190967	69	75.36	1	69	1	69	2.0e-20	90.7	COG2053	Ribosomal protein S28E/S33	69
638190968	66	53.03	1	66	1	65	4.0e-19	86.2	COG2075	Ribosomal protein L24E	66
638190969	147	54.48	1	134	2	135	6.0e-54	203	COG0105	Nucleoside diphosphate kinase	135
638190970	589	31.05	12	560	1	509	2.0e-118	419	COG0532	Translation initiation factor 2 (IF-2; GTPase)	509
638190971	317	25.16	1	311	2	314	7.0e-40	157	COG0451	Nucleoside-diphosphate-sugar epimerases	314
638190972	359	38.24	2	357	2	375	4.0e-124	438	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
638190973	171	47.37	1	171	1	167	8.0e-54	203	COG2150	Predicted regulator of amino acid metabolism, contains ACT domain	167
638190975	323	32.86	49	321	1	266	1.0e-71	263	COG0468	RecA/RadA recombinase	279
638190976	338	24.64	1	320	1	335	2.0e-71	263	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
638190979	182	54.59	1	181	3	187	2.0e-73	268	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
638190980	157	40	6	157	1	164	9.0e-42	162	COG1656	Uncharacterized conserved protein	165
638190981	340	39.38	1	339	1	352	3.0e-92	332	COG1537	Predicted RNA-binding proteins	352
638190986	237	19.46	18	199	1	179	2.0e-06	46.6	COG0732	Restriction endonuclease S subunits	391
638190987	291	24.39	11	284	122	402	5.0e-27	115	COG3464	Transposase and inactivated derivatives	402
638190989	295	20.14	7	285	1	274	1.0e-18	87.4	COG0675	Transposase and inactivated derivatives	364
638190990	121	41.94	2	121	1	124	4.0e-34	136	COG1943	Transposase and inactivated derivatives	136
638190991	122	39.19	36	107	1	74	6.0e-15	73	COG0492	Thioredoxin reductase	305
638190993	423	19.53	13	224	1	196	3.0e-12	66.6	COG2391	Predicted transporter component	198
638190994	388	19.07	5	370	1	372	1.0e-38	154	COG0446	Uncharacterized NAD(FAD)-dependent dehydrogenases	415
638190996	240	40.16	3	240	2	250	5.0e-65	241	COG1801	Uncharacterized conserved protein	263
638190997	402	21.23	9	216	1	191	3.0e-08	53.5	COG2391	Predicted transporter component	198
638190999	418	28.17	1	418	5	407	4.0e-104	371	COG2235	Arginine deiminase	409
638191000	335	33.43	1	335	7	350	1.0e-86	313	COG1499	NMD protein affecting ribosome stability and mRNA decay	355
638191001	205	41.58	8	197	3	181	4.0e-33	134	COG3371	Predicted membrane protein	181
638191002	360	45.33	1	360	1	372	0.0e+00	474	COG1415	Uncharacterized conserved protein	373
638191003	100	51	1	100	4	103	1.0e-36	144	COG4847	Uncharacterized protein conserved in archaea	103
638191004	55	64	1	50	2	51	5.0e-15	72.7	COG1998	Ribosomal protein S27AE	51
638191005	99	43.43	1	99	1	99	2.0e-21	93.8	COG2004	Ribosomal protein S24E	107
638191006	166	46.99	5	166	1	166	3.0e-47	181	COG1909	Uncharacterized protein conserved in archaea	167
638191007	64	57.81	2	63	1	64	5.0e-20	89.2	COG2093	DNA-directed RNA polymerase, subunit E''	64
638191008	195	52.08	4	195	1	182	9.0e-57	213	COG1095	DNA-directed RNA polymerase, subunit E'	183
638191009	365	44.89	1	364	2	362	8.0e-116	410	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
638191010	613	54.25	1	582	4	579	0.0e+00	589	COG0443	Molecular chaperone	579
638191011	176	31.41	4	176	2	192	5.0e-29	120	COG0576	Molecular chaperone GrpE (heat shock protein)	193
638191012	410	19.28	33	366	33	392	9.0e-06	45.2	COG2211	Na+/melibiose symporter and related transporters	467
638191013	148	42.11	1	147	23	174	3.0e-45	174	COG1881	Phospholipid-binding protein	174
638191014	439	35.62	11	433	4	436	3.0e-110	392	COG1030	Membrane-bound serine protease (ClpP class)	436
638191015	113	79.65	1	113	1	108	3.0e-41	160	COG3373	Uncharacterized protein conserved in archaea	108
638191016	655	42.4	6	644	2	647	0.0e+00	643	COG1067	Predicted ATP-dependent protease	647
638191018	259	29.27	2	242	1	246	2.0e-41	162	COG0368	Cobalamin-5-phosphate synthase	246
638191019	345	23.64	1	342	7	391	4.0e-44	172	COG0436	Aspartate/tyrosine/aromatic aminotransferase	393
638191020	274	25.56	1	256	16	282	3.0e-35	142	COG0731	Fe-S oxidoreductases	296
638191022	160	60.62	1	160	3	162	3.0e-69	254	COG1839	Uncharacterized conserved protein	162
638191023	531	57.61	20	530	1	515	0.0e+00	737	COG1243	Histone acetyltransferase	515
638191024	585	41.13	20	579	1	560	0.0e+00	632	COG2060	K+-transporting ATPase, A chain	560
638191025	668	52.51	2	667	6	681	0.0e+00	936	COG2216	High-affinity K+ transport system, ATPase chain B	681
638191026	209	31.82	1	194	1	190	2.0e-53	202	COG2156	K+-transporting ATPase, c chain	190
638191029	329	47.75	2	329	2	333	3.0e-123	435	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
638191030	291	40.6	3	290	1	297	2.0e-99	355	COG1090	Predicted nucleoside-diphosphate sugar epimerase	297
638191031	312	43.54	27	312	1	278	5.0e-83	301	COG0731	Fe-S oxidoreductases	296
638191032	544	44.65	11	532	1	523	0.0e+00	490	COG0459	Chaperonin GroEL (HSP60 family)	524
638191033	211	39.52	2	206	1	209	6.0e-51	193	COG0352	Thiamine monophosphate synthase	211
638191034	374	35.82	22	365	1	339	2.0e-99	356	COG0309	Hydrogenase maturation factor	339
638191035	517	23.29	9	505	6	462	6.0e-25	109	COG0531	Amino acid transporters	466
638191036	306	26.58	8	305	1	316	3.0e-67	248	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638191037	257	38.22	1	255	2	252	1.0e-73	269	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
638191038	266	54.2	1	261	1	262	1.0e-95	342	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
638191039	226	53.88	1	226	10	241	8.0e-89	319	COG1709	Predicted transcriptional regulator	241
638191040	418	31.65	1	405	2	414	2.0e-84	306	COG0402	Cytosine deaminase and related metal-dependent hydrolases	421
638191041	155	26.77	8	125	14	137	3.0e-09	54.8	COG1695	Predicted transcriptional regulators	138
638191042	481	19.5	5	444	9	388	7.0e-13	69.1	COG2814	Arabinose efflux permease	394
638191043	533	26.59	8	516	2	500	1.0e-48	188	COG1361	S-layer domain	500
638191045	206	33.33	144	205	153	215	4.0e-08	51.6	COG3413	Predicted DNA binding protein	215
638191046	220	58.14	7	220	2	214	1.0e-75	276	COG1339	Transcriptional regulator of a riboflavin/FAD biosynthetic operon	214
638191048	759	43.4	4	753	1	743	0.0e+00	876	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
638191049	362	25.13	1	360	1	378	5.0e-32	132	COG0438	Glycosyltransferase	381
638191050	348	50.84	1	347	2	355	2.0e-114	405	COG3199	Uncharacterized conserved protein	355
638191052	203	34.16	2	203	2	203	8.0e-35	140	COG2095	Multiple antibiotic transporter	203
638191054	279	36.71	1	272	4	289	6.0e-61	227	COG1131	ABC-type multidrug transport system, ATPase component	293
638191055	390	23.72	1	369	1	314	2.0e-30	126	COG0451	Nucleoside-diphosphate-sugar epimerases	314
638191056	246	32.16	3	246	1	245	9.0e-58	216	COG1209	dTDP-glucose pyrophosphorylase	286
638191057	408	40.63	1	404	1	395	1.0e-123	436	COG0126	3-phosphoglycerate kinase	395
638191058	130	33.33	3	130	9	143	1.0e-20	92.3	COG1730	Predicted prefoldin, molecular chaperone implicated in de novo protein folding	145
638191059	287	47.51	1	282	40	340	2.0e-94	338	COG0552	Signal recognition particle GTPase	340
638191060	107	36.84	2	106	10	123	2.0e-18	84.2	COG0073	EMAP domain	123
638191061	420	15.01	13	360	1	322	1.0e-17	84.6	COG0470	ATPase involved in DNA replication	324
638191062	197	61.03	3	197	1	195	9.0e-65	239	COG1632	Ribosomal protein L15E	195
638191064	299	28.12	41	168	79	206	2.0e-17	83.5	COG0726	Predicted xylanase/chitin deacetylase	267
638191065	129	34.13	3	126	1	125	5.0e-29	119	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
638191066	303	40.67	17	298	6	304	7.0e-64	237	COG0010	Arginase/agmatinase/formimionoglutamate hydrolase, arginase family	305
638191067	176	29.87	11	164	1	136	8.0e-32	129	COG0197	Ribosomal protein L16/L10E	146
638191069	641	56.19	1	641	1	635	0.0e+00	923	COG0187	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit	635
638191070	792	49.37	2	792	9	800	0.0e+00	918	COG0188	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit	804
638191071	208	23.58	13	206	1	205	3.0e-25	108	COG1335	Amidases related to nicotinamidase	205
638191072	389	20.74	9	358	1	258	8.0e-35	141	COG0725	ABC-type molybdate transport system, periplasmic component	258
638191073	251	30.59	1	251	21	272	2.0e-47	182	COG0555	ABC-type sulfate transport system, permease component	274
638191074	294	35.81	12	233	19	247	7.0e-56	210	COG3839	ABC-type sugar transport systems, ATPase components	338
638191075	250	19.56	7	247	57	326	4.0e-18	85.4	COG1215	Glycosyltransferases, probably involved in cell wall biogenesis	439
638191078	114	28.45	6	113	9	123	9.0e-15	72.3	COG0073	EMAP domain	123
638191079	74	44.3	1	73	2	80	2.0e-16	77.1	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
638191080	575	45.56	2	575	1	578	0.0e+00	605	COG3356	Predicted membrane protein	578
638191081	210	43.72	1	210	10	223	3.0e-50	191	COG1711	Uncharacterized protein conserved in archaea	223
638191082	119	39.67	1	115	1	121	1.0e-24	104	COG1433	Uncharacterized conserved protein	121
638191083	127	64.57	1	127	1	127	2.0e-41	161	COG2007	Ribosomal protein S8E	127
638191084	84	39.53	1	84	2	87	8.0e-16	75.3	COG1400	Signal recognition particle 19 kDa protein	93
638191085	327	37.54	14	327	24	356	4.0e-76	278	COG2219	Eukaryotic-type DNA primase, large subunit	363
638191086	360	37.57	1	360	8	384	8.0e-84	304	COG0006	Xaa-Pro aminopeptidase	384
638191087	234	23.46	2	232	30	270	2.0e-47	182	COG0468	RecA/RadA recombinase	279
638191088	335	27.68	11	335	1	308	4.0e-46	179	COG0258	5'-3' exonuclease (including N-terminal domain of PolI)	310
638191089	415	16.75	12	405	14	390	1.0e-07	51.4	COG2814	Arabinose efflux permease	394
638191090	171	36.62	31	170	1	121	2.0e-30	125	COG0099	Ribosomal protein S13	121
638191091	200	24.75	1	200	1	188	2.0e-33	135	COG0522	Ribosomal protein S4 and related proteins	205
638191092	127	48.36	3	124	17	129	8.0e-32	129	COG0100	Ribosomal protein S11	129
638191093	271	23.1	1	267	5	314	3.0e-42	165	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
638191095	391	37.22	1	391	6	402	2.0e-102	366	COG0303	Molybdopterin biosynthesis enzyme	404
638191096	629	37.16	5	408	1	403	2.0e-108	387	COG0303	Molybdopterin biosynthesis enzyme	404
638191096	629	46.4	415	629	1	221	7.0e-71	262	COG1910	Periplasmic molybdate-binding protein/domain	223
638191097	263	21.64	91	246	94	264	3.0e-08	52.6	COG1091	dTDP-4-dehydrorhamnose reductase	281
638191098	90	35.71	12	90	1	84	3.0e-13	66.9	COG1977	Molybdopterin converting factor, small subunit	84
638191099	224	33.18	7	224	66	285	2.0e-49	188	COG1405	Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB	285
638191100	380	38.38	3	377	6	383	2.0e-105	375	COG0075	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase	383
638191101	410	40.73	2	410	2	396	2.0e-120	426	COG3372	Uncharacterized conserved protein	396
638191102	455	40.56	41	443	1	406	8.0e-88	317	COG1061	DNA or RNA helicases of superfamily II	442
638191104	195	53.89	1	192	2	193	2.0e-69	255	COG0807	GTP cyclohydrolase II	193
638191105	194	33.68	1	181	1	188	3.0e-29	121	COG1014	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit	203
638191106	604	51.57	1	603	10	639	0.0e+00	772	COG4231	Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	640
638191107	268	28.96	8	186	1	168	1.0e-36	147	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerases 2	174
638191108	250	40.83	7	240	1	238	2.0e-72	265	COG0565	rRNA methylase	242
638191109	107	45.87	1	107	4	112	1.0e-29	121	COG1416	Uncharacterized conserved protein	112
638191111	529	27.27	1	485	2	490	1.0e-58	220	COG1032	Fe-S oxidoreductase	490
638191114	401	28.21	175	280	30	135	4.0e-07	49.5	COG3642	Mn2+-dependent serine/threonine protein kinase	204
638191115	257	38.13	2	253	1	255	1.0e-73	270	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
638191116	227	32.39	1	225	4	238	3.0e-52	198	COG0528	Uridylate kinase	238
638191120	418	57.28	4	412	1	411	0.0e+00	507	COG1503	Peptide chain release factor 1 (eRF1)	411
638191121	309	39.53	23	296	9	299	2.0e-74	272	COG0031	Cysteine synthase	300
638191122	409	29.16	3	380	1	414	7.0e-93	334	COG0373	Glutamyl-tRNA reductase	414
638191123	249	38.17	4	243	1	235	4.0e-69	254	COG1407	Predicted ICC-like phosphoesterases	235
638191124	381	45.5	1	372	18	384	0.0e+00	508	COG1139	Uncharacterized conserved protein containing a ferredoxin-like domain	459
638191125	300	18.13	2	300	51	386	9.0e-29	120	COG0247	Fe-S oxidoreductase	388
638191126	403	18.16	17	396	28	391	1.0e-15	77.9	COG2814	Arabinose efflux permease	394
638191127	381	20.3	4	370	1	363	3.0e-42	166	COG0247	Fe-S oxidoreductase	388
638191128	459	38.26	12	458	8	456	1.0e-92	333	COG0277	FAD/FMN-containing dehydrogenases	459
638191130	146	41.89	1	146	5	151	7.0e-44	169	COG0241	Histidinol phosphatase and related phosphatases	181
638191131	437	39.91	1	436	3	421	0.0e+00	462	COG1571	Predicted DNA-binding protein containing a Zn-ribbon domain	421
638191132	258	54.27	25	258	13	244	1.0e-85	309	COG0020	Undecaprenyl pyrophosphate synthase	245
638191135	327	54.49	1	323	3	321	2.0e-122	432	COG3888	Predicted transcriptional regulator	321
638191136	107	26.26	4	102	2	89	6.0e-08	49.3	COG3609	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain	89
638191137	537	25.35	1	537	1	551	2.0e-96	346	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
638191138	169	54.55	1	164	12	176	1.0e-52	198	COG0663	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily	176
638191139	247	46.05	17	244	1	206	8.0e-47	180	COG1681	Archaeal flagellins	209
638191140	157	71.97	4	157	1	157	3.0e-34	137	COG3352	Putative archaeal flagellar protein C	157
638191141	217	68.98	6	217	1	214	2.0e-63	235	COG3351	Putative archaeal flagellar protein D/E	214
638191142	137	59.85	1	137	1	137	3.0e-36	143	COG3353	Putative archaeal flagellar protein F	137
638191143	147	55.84	1	147	1	154	9.0e-40	155	COG3354	Putative archaeal flagellar protein G	154
638191144	223	44.25	5	223	10	235	2.0e-71	262	COG2874	Predicted ATPases involved in biogenesis of archaeal flagella	235
638191145	535	50.8	143	455	1	311	6.0e-93	335	COG0630	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	312
638191146	552	48.87	24	552	1	525	0.0e+00	551	COG1955	Archaeal flagella assembly protein J	527
638191148	192	30.21	4	192	1	190	9.0e-14	70	COG1994	Zn-dependent proteases	230
638191149	352	21.73	1	339	17	374	4.0e-28	118	COG1215	Glycosyltransferases, probably involved in cell wall biogenesis	439
638191150	91	47.73	4	91	1	88	4.0e-16	76.4	COG2092	Translation elongation factor EF-1beta	88
638191151	55	50	1	55	6	61	1.0e-12	64.6	COG2888	Predicted Zn-ribbon RNA-binding protein with a function in translation	61
638191152	447	40.91	1	446	4	464	7.0e-116	410	COG1109	Phosphomannomutase	464
638191153	199	29.67	22	199	12	189	2.0e-13	69.7	COG0558	Phosphatidylglycerophosphate synthase	192
638191154	153	39.13	3	153	1	161	2.0e-42	164	COG1936	Predicted nucleotide kinase (related to CMP and AMP kinases)	180
638191155	445	32.26	17	444	10	438	2.0e-79	290	COG1457	Purine-cytosine permease and related proteins	442
638191156	171	27.43	6	171	4	176	2.0e-27	115	COG1386	Predicted transcriptional regulator containing the HTH domain	184
638191157	435	37.39	4	427	2	428	3.0e-127	448	COG0151	Phosphoribosylamine-glycine ligase	428
638191158	89	45.45	1	88	6	93	1.0e-28	118	COG1698	Uncharacterized protein conserved in archaea	93
638191159	120	52.5	1	120	5	124	7.0e-40	155	COG4738	Predicted transcriptional regulator	124
638191160	666	15.36	75	390	101	414	7.0e-06	46.6	COG1287	Uncharacterized membrane protein, required for N-linked glycosylation	773
638191162	614	49.64	3	413	11	423	0.0e+00	472	COG1239	Mg-chelatase subunit ChlI	423
638191163	305	49.52	1	305	4	313	3.0e-114	404	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
638191164	152	54.61	1	152	2	152	2.0e-54	204	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
638191165	232	27.85	11	230	12	248	6.0e-34	137	COG1587	Uroporphyrinogen-III synthase	248
638191166	297	39.27	1	296	2	300	1.0e-84	306	COG0181	Porphobilinogen deaminase	307
638191167	420	52.94	1	419	5	429	0.0e+00	592	COG0001	Glutamate-1-semialdehyde aminotransferase	432
638191168	157	34.44	1	153	1	180	3.0e-35	141	COG0717	Deoxycytidine deaminase	183
638191169	165	43.51	1	154	4	157	1.0e-46	179	COG1607	Acyl-CoA hydrolase	157
638191172	664	14.38	29	664	1	508	1.0e-06	48.8	COG0433	Predicted ATPase	520
638191174	326	24.05	3	326	8	335	6.0e-66	244	COG1077	Actin-like ATPase involved in cell morphogenesis	342
638191176	115	44.83	1	115	1	113	9.0e-30	121	COG3370	Uncharacterized protein conserved in archaea	113
638191177	278	30.69	2	277	1	258	2.0e-18	86.6	COG0730	Predicted permeases	258
638191178	1713	49.64	10	848	1	801	0.0e+00	942	COG1201	Lhr-like helicases	814
638191179	150	29.8	1	146	5	154	2.0e-15	75	COG0589	Universal stress protein UspA and related nucleotide-binding proteins	154
638191180	75	52.7	1	74	1	74	5.0e-17	79.2	COG1383	Ribosomal protein S17E	74
638191182	388	40.66	1	379	1	383	2.0e-84	306	COG0183	Acetyl-CoA acetyltransferase	392
638191183	417	24.37	1	388	3	368	1.0e-47	184	COG0665	Glycine/D-amino acid oxidases (deaminating)	387
638191184	234	33.16	42	231	16	208	4.0e-32	131	COG0586	Uncharacterized membrane-associated protein	208
638191185	98	34.65	1	98	1	100	6.0e-18	82.3	COG2329	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides	105
638191186	515	36.71	40	510	1	464	3.0e-108	385	COG1012	NAD-dependent aldehyde dehydrogenases	472
638191187	514	20.29	2	479	8	480	5.0e-21	96.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
638191188	208	47.83	137	205	5	73	6.0e-17	80.7	COG3269	Predicted RNA-binding protein, contains TRAM domain	73
638191188	208	47.14	1	138	4	143	1.0e-36	146	COG1601	Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain	151
638191190	244	22.27	26	243	8	214	1.0e-35	143	COG0206	Cell division GTPase	338
638191191	143	28.67	1	143	6	147	2.0e-24	104	COG1522	Transcriptional regulators	154
638191192	314	34.64	2	314	110	435	7.0e-82	297	COG0017	Aspartyl/asparaginyl-tRNA synthetases	435
638191193	200	21.66	1	197	136	351	5.0e-15	74.3	COG0417	DNA polymerase elongation subunit (family B)	792
638191194	473	16.67	8	426	13	378	8.0e-09	55.6	COG2814	Arabinose efflux permease	394
638191195	140	32.73	15	123	161	269	2.0e-16	78	COG2905	Predicted signal-transduction protein containing cAMP-binding and CBS domains	610
638191196	211	44.39	1	211	23	236	8.0e-54	203	COG0638	20S proteasome, alpha and beta subunits	236
638191197	639	61.93	1	639	1	637	0.0e+00	1025	COG1782	Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain	637
638191199	223	51.77	1	215	8	233	2.0e-68	252	COG0176	Transaldolase	239
638191200	316	61.36	2	307	5	312	1.0e-128	453	COG3958	Transketolase, C-terminal subunit	312
638191201	273	59.34	1	239	3	243	3.0e-101	361	COG3959	Transketolase, N-terminal subunit	243
638191202	288	28.17	5	277	9	290	3.0e-54	205	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
638191203	420	36.27	2	391	1	389	1.0e-83	304	COG1960	Acyl-CoA dehydrogenases	393
638191204	518	30.68	1	518	5	528	1.0e-94	340	COG0318	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II	534
638191206	122	51.85	7	112	1	108	9.0e-30	122	COG0393	Uncharacterized conserved protein	108
638191207	509	19.88	4	509	287	792	8.0e-79	287	COG0249	Mismatch repair ATPase (MutS family)	843
638191208	500	19.68	5	500	289	786	2.0e-80	293	COG0249	Mismatch repair ATPase (MutS family)	843
638191209	233	39.9	24	228	6	206	5.0e-64	237	COG2191	Formylmethanofuran dehydrogenase subunit E	206
638191211	250	29.6	1	247	3	252	3.0e-11	62.7	COG0730	Predicted permeases	258
638191215	214	26.36	103	198	79	181	4.0e-06	45.2	COG4974	Site-specific recombinase XerD	300
638191216	985	15.5	87	969	13	786	1.0e-54	208	COG1002	Type II restriction enzyme, methylase subunits	786
638191217	1043	15.51	214	1011	85	833	1.0e-10	62.5	COG0553	Superfamily II DNA/RNA helicases, SNF2 family	866
638191220	481	32.06	3	468	1	460	6.0e-108	384	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
638191221	416	20.82	27	398	23	402	9.0e-31	128	COG3464	Transposase and inactivated derivatives	402
638191223	647	36.48	9	640	1	587	0.0e+00	706	COG3934	Endo-beta-mannanase	587
638191229	89	23.81	1	63	202	264	2.0e-06	44.2	COG3385	FOG: Transposase and inactivated derivatives	292
638191232	200	35.5	4	198	3	200	6.0e-31	127	COG1961	Site-specific recombinases, DNA invertase Pin homologs	222
638191233	89	32.35	22	88	4	71	3.0e-07	46.9	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
638191239	187	23.57	55	186	144	280	2.0e-09	56.1	COG3378	Predicted ATPase	517
638191244	220	30.95	3	219	7	253	2.0e-35	142	COG0631	Serine/threonine protein phosphatase	262
638191245	229	38.94	14	220	1	226	1.0e-64	239	COG1489	DNA-binding protein, stimulates sugar fermentation	235
638191246	288	19.39	4	287	1	287	2.0e-16	80.3	COG0668	Small-conductance mechanosensitive channel	316
638191247	133	36.92	8	132	7	135	7.0e-26	109	COG0824	Predicted thioesterase	137
638191249	529	20.81	1	469	1	458	1.0e-21	98.3	COG0531	Amino acid transporters	466
638191252	1365	33.73	18	1365	1	1174	0.0e+00	830	COG4934	Predicted protease	1174
638191253	256	34.24	1	252	1	251	1.0e-38	153	COG1028	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	251
638191256	390	25.86	5	343	11	342	1.0e-29	124	COG0675	Transposase and inactivated derivatives	364
638191258	186	19.51	1	186	1	205	1.0e-11	63.4	COG1280	Putative threonine efflux protein	208
638191259	142	29.05	1	142	6	152	5.0e-16	76.9	COG0589	Universal stress protein UspA and related nucleotide-binding proteins	154
638191260	241	52.68	2	222	1	221	1.0e-70	259	COG0120	Ribose 5-phosphate isomerase	227
638191261	476	26.67	1	457	1	449	3.0e-22	99.8	COG0531	Amino acid transporters	466
638191262	186	47.49	7	184	1	179	4.0e-52	197	COG2110	Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1	179
638191270	257	27.37	4	257	28	300	1.0e-65	242	COG3440	Predicted restriction endonuclease	301
638191271	196	22.82	5	194	106	292	1.0e-13	69.9	COG4974	Site-specific recombinase XerD	300
638191275	165	38.12	2	165	1	171	2.0e-31	128	COG3465	Uncharacterized conserved protein	171
638191281	123	33.33	1	123	144	272	8.0e-19	86	COG4974	Site-specific recombinase XerD	300
638191283	305	34.39	1	304	2	312	1.0e-57	216	COG0657	Esterase/lipase	312
638191285	315	38.44	2	306	5	299	4.0e-57	215	COG1940	Transcriptional regulator/sugar kinase	314
638191286	366	46.24	3	356	2	357	0.0e+00	466	COG0082	Chorismate synthase	369
638191287	189	31.77	1	172	2	192	3.0e-33	134	COG0406	Fructose-2,6-bisphosphatase	208
638191288	647	40.65	1	646	6	667	0.0e+00	760	COG1331	Highly conserved protein containing a thioredoxin domain	667
638191289	458	32.01	1	449	2	448	2.0e-111	396	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
638191291	245	46.86	1	239	9	240	3.0e-76	278	COG1646	Predicted phosphate-binding enzymes, TIM-barrel fold	240
638191292	269	23.44	4	269	17	286	7.0e-28	117	COG0382	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases	289
638191293	342	43.88	1	342	4	379	2.0e-113	402	COG1867	N2,N2-dimethylguanosine tRNA methyltransferase	380
638191294	178	46.63	1	178	4	179	4.0e-53	200	COG1618	Predicted nucleotide kinase	179
638191295	120	61.54	4	120	1	116	3.0e-47	180	COG2098	Uncharacterized protein conserved in archaea	116
638191296	885	23.64	5	590	19	626	5.0e-54	206	COG0210	Superfamily I DNA and RNA helicases	655
638191297	404	45.55	16	404	5	392	2.0e-122	432	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
638191299	106	43.24	7	106	3	113	1.0e-22	98.2	COG1594	DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS	113
638191300	141	48.53	3	136	1	136	4.0e-45	173	COG1832	Predicted CoA-binding protein	140
638191302	123	29.06	1	117	4	117	3.0e-19	87.2	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
638191303	140	26.32	10	136	3	132	7.0e-12	63	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
638191304	240	47.66	3	236	1	234	1.0e-80	292	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
638191305	567	52.2	2	558	3	562	0.0e+00	604	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
638191307	150	43.06	7	149	14	150	3.0e-45	174	COG0315	Molybdenum cofactor biosynthesis enzyme	157
638191308	134	35.94	11	132	3	130	2.0e-18	84.5	COG1943	Transposase and inactivated derivatives	136
638191309	162	36.09	7	162	1	169	2.0e-36	145	COG0521	Molybdopterin biosynthesis enzymes	169
638191311	340	34.73	1	340	2	376	6.0e-73	267	COG0498	Threonine synthase	411
638191312	150	35.71	1	150	8	161	2.0e-29	121	COG3430	Uncharacterized protein conserved in archaea	161
638191315	236	40.93	2	236	1	234	6.0e-63	234	COG2872	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	241
638191316	407	40	2	400	30	427	1.0e-115	410	COG0285	Folylpolyglutamate synthase	427
638191317	429	42.18	37	413	1	366	7.0e-92	331	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
638191318	435	60.92	24	435	1	411	0.0e+00	571	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638191319	416	60.1	6	416	2	411	0.0e+00	574	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638191320	897	27.78	5	849	9	805	0.0e+00	634	COG0495	Leucyl-tRNA synthetase	814
638191321	182	52.2	1	182	1	163	4.0e-53	200	COG1945	Uncharacterized conserved protein	163
638191325	485	24.07	6	455	2	445	6.0e-20	92.5	COG0531	Amino acid transporters	466
638191326	416	19.58	12	388	8	349	7.0e-29	122	COG0675	Transposase and inactivated derivatives	364
638191327	143	26.74	7	143	2	188	7.0e-34	136	COG2452	Predicted site-specific integrase-resolvase	193
638191329	301	37.5	212	289	77	156	2.0e-07	50.4	COG0456	Acetyltransferases	177
638191330	451	45.21	2	435	4	432	0.0e+00	518	COG0281	Malic enzyme	432
638191331	148	33.87	80	140	91	152	6.0e-07	46.9	COG0456	Acetyltransferases	177
638191332	303	26.95	31	280	109	351	1.0e-22	100	COG0675	Transposase and inactivated derivatives	364
638191333	175	34.88	1	152	4	175	4.0e-30	124	COG1335	Amidases related to nicotinamidase	205
638191335	565	62.16	22	563	3	548	0.0e+00	785	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
638191336	146	44.2	6	143	6	143	1.0e-36	145	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
638191337	315	44.27	1	308	2	323	5.0e-107	381	COG1703	Putative periplasmic protein kinase ArgK and related GTPases of G3E family	323
638191338	124	25.53	1	124	6	146	1.0e-15	75.4	COG0071	Molecular chaperone (small heat shock protein)	146
638191339	510	35.51	1	510	6	517	1.0e-119	423	COG0661	Predicted unusual protein kinase	517
638191340	110	27.62	4	105	28	130	8.0e-13	65.7	COG3118	Thioredoxin domain-containing protein	304
638191343	159	58.86	2	159	1	156	6.0e-50	189	COG3612	Uncharacterized protein conserved in archaea	157
638191345	321	30.37	113	317	3	212	1.0e-49	190	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
638191345	321	33.33	15	100	11	95	2.0e-11	63.8	COG3695	Predicted methylated DNA-protein cysteine methyltransferase	103
638191346	350	30.51	21	343	4	329	2.0e-80	292	COG3407	Mevalonate pyrophosphate decarboxylase	329
638191347	420	35.29	12	418	2	422	1.0e-126	447	COG2379	Putative glycerate kinase	422
638191348	500	23.38	1	500	2	534	3.0e-90	326	COG0028	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]	550
638191349	166	31.79	1	166	12	184	4.0e-30	124	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
638191350	143	34.85	13	143	7	138	4.0e-15	74	COG3431	Predicted membrane protein	142
638191351	522	17.58	1	455	6	428	3.0e-06	47.1	COG0531	Amino acid transporters	466
638191354	476	26.74	376	455	5	90	2.0e-08	54.5	COG0607	Rhodanese-related sulfurtransferase	110
638191354	476	39.69	1	374	2	383	6.0e-107	381	COG0301	Thiamine biosynthesis ATP pyrophosphatase	383
638191355	223	41.07	3	222	9	230	3.0e-69	255	COG3253	Uncharacterized conserved protein	230
638191356	347	47.52	18	338	1	320	1.0e-88	319	COG0206	Cell division GTPase	338
638191357	219	36.84	10	217	1	200	6.0e-52	197	COG1865	Uncharacterized conserved protein	200
638191358	91	33.33	2	91	1	84	2.0e-14	70.7	COG1977	Molybdopterin converting factor, small subunit	84
638191359	603	52.21	4	601	3	612	0.0e+00	753	COG2414	Aldehyde:ferredoxin oxidoreductase	614
638191360	389	31.94	2	386	10	413	2.0e-113	402	COG0112	Glycine/serine hydroxymethyltransferase	413
638191361	355	36.44	1	107	251	368	6.0e-14	71.9	COG3448	CBS-domain-containing membrane protein	382
638191362	444	33.41	7	443	23	451	6.0e-86	311	COG0312	Predicted Zn-dependent proteases and their inactivated homologs	454
638191363	431	23.3	2	429	1	453	7.0e-64	238	COG0312	Predicted Zn-dependent proteases and their inactivated homologs	454
638191364	779	33.85	3	779	24	858	0.0e+00	597	COG0308	Aminopeptidase N	859
638191365	464	23.86	5	180	13	188	2.0e-08	54.1	COG2814	Arabinose efflux permease	394
638191366	345	43.99	1	345	2	365	9.0e-118	416	COG0505	Carbamoylphosphate synthase small subunit	368
638191367	1044	60.56	13	402	1	392	0.0e+00	501	COG0458	Carbamoylphosphate synthase large subunit (split gene in MJ)	400
638191368	215	39.71	4	210	1	209	2.0e-73	268	COG0177	Predicted EndoIII-related endonuclease	211
638191369	590	29.87	9	456	7	441	4.0e-28	120	COG0531	Amino acid transporters	466
638191370	409	39.34	4	380	1	394	2.0e-97	349	COG0019	Diaminopimelate decarboxylase	394
638191371	1141	30.57	4	1137	2	1163	0.0e+00	585	COG1196	Chromosome segregation ATPases	1163
638191372	250	20	7	250	1	241	3.0e-28	118	COG1354	Uncharacterized conserved protein	248
638191373	197	40.96	7	192	2	180	1.0e-28	119	COG3371	Predicted membrane protein	181
638191374	429	22.01	53	389	66	411	2.0e-09	57.5	COG2271	Sugar phosphate permease	448
638191375	533	46.04	5	532	8	536	0.0e+00	677	COG0146	N-methylhydantoinase B/acetone carboxylase, alpha subunit	563
638191376	656	42.94	5	656	3	674	0.0e+00	604	COG0145	N-methylhydantoinase A/acetone carboxylase, beta subunit	674
638191377	290	21.37	1	290	62	412	1.0e-28	120	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes	438
638191380	674	40.69	2	665	10	729	0.0e+00	603	COG1204	Superfamily II helicase	766
638191381	307	42.86	3	303	2	337	1.0e-78	286	COG2520	Predicted methyltransferase	341
638191382	435	31.6	3	416	1	415	1.0e-59	224	COG0446	Uncharacterized NAD(FAD)-dependent dehydrogenases	415
638191383	894	36.36	1	794	1	814	0.0e+00	832	COG1201	Lhr-like helicases	814
638191385	878	30.91	59	849	3	830	0.0e+00	687	COG0013	Alanyl-tRNA synthetase	879
638191386	140	37.23	1	137	27	162	5.0e-42	163	COG1956	GAF domain-containing protein	163
638191387	297	21.74	10	292	9	282	6.0e-14	71.8	COG0668	Small-conductance mechanosensitive channel	316
638191388	430	16.11	22	397	22	435	9.0e-06	45.2	COG2211	Na+/melibiose symporter and related transporters	467
638191389	800	33.79	11	775	1	792	0.0e+00	565	COG0417	DNA polymerase elongation subunit (family B)	792
638191390	301	36.08	1	299	4	319	1.0e-71	263	COG2423	Predicted ornithine cyclodeaminase, mu-crystallin homolog	330
638191391	343	26.5	1	333	233	597	1.0e-78	287	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
638191392	294	45.05	1	292	1	285	3.0e-92	331	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638191393	227	29.07	1	227	3	201	3.0e-37	148	COG1573	Uracil-DNA glycosylase	202
638191394	423	22.92	1	421	3	416	7.0e-52	198	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
638191395	1028	38.06	17	959	22	933	0.0e+00	969	COG0060	Isoleucyl-tRNA synthetase	933
638191396	208	40.78	105	203	8	110	3.0e-15	75.3	COG0607	Rhodanese-related sulfurtransferase	110
638191398	188	31.22	1	179	2	189	1.0e-28	119	COG0406	Fructose-2,6-bisphosphatase	208
638191399	185	34.2	4	182	3	193	7.0e-35	140	COG1014	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit	203
638191400	95	43.16	1	95	8	91	2.0e-22	97	COG1144	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit	91
638191401	392	36.39	8	374	3	359	1.0e-90	326	COG0674	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit	365
638191402	295	33.89	4	291	3	294	6.0e-75	274	COG1013	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit	294
638191403	185	31.58	23	132	41	154	3.0e-17	81.5	COG2226	Methylase involved in ubiquinone/menaquinone biosynthesis	238
638191404	370	33.06	1	367	9	347	7.0e-57	214	COG0535	Predicted Fe-S oxidoreductases	347
638191405	150	34	1	150	1	146	9.0e-43	165	COG3427	Uncharacterized conserved protein	146
638191406	414	26.41	1	413	12	451	4.0e-91	328	COG0578	Glycerol-3-phosphate dehydrogenase	532
638191407	161	20.96	14	161	89	255	7.0e-15	73.3	COG0584	Glycerophosphoryl diester phosphodiesterase	257
638191408	434	22.93	7	377	1	353	3.0e-36	146	COG0675	Transposase and inactivated derivatives	364
638191409	134	41.91	2	133	1	136	7.0e-38	149	COG1943	Transposase and inactivated derivatives	136
638191411	193	51.16	19	188	1	172	4.0e-56	210	COG1056	Nicotinamide mononucleotide adenylyltransferase	172
638191412	629	31.41	228	619	1	365	9.0e-78	284	COG0674	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit	365
638191413	309	37.54	7	303	9	294	4.0e-81	294	COG1013	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit	294
638191414	390	37.08	15	390	3	389	4.0e-99	355	COG0436	Aspartate/tyrosine/aromatic aminotransferase	393
638191415	277	46.93	7	277	1	272	3.0e-70	258	COG0338	Site-specific DNA methylase	274
638191416	223	36.59	2	223	6	250	2.0e-36	145	COG2220	Predicted Zn-dependent hydrolases of the beta-lactamase fold	258
638191417	121	39.2	2	121	6	130	3.0e-24	103	COG1412	Uncharacterized proteins of PilT N-term./Vapc superfamily	136
638191418	208	45.24	3	208	84	293	6.0e-70	257	COG2074	2-phosphoglycerate kinase	299
638191419	194	16.75	9	192	1	203	3.0e-14	71.8	COG1335	Amidases related to nicotinamidase	205
638191420	251	22.82	8	241	4	236	2.0e-14	73.3	COG0463	Glycosyltransferases involved in cell wall biogenesis	291
638191422	516	50.76	3	327	5	326	7.0e-111	394	COG1796	DNA polymerase IV (family X)	326
638191424	218	44.5	2	218	1	218	2.0e-65	242	COG1878	Predicted metal-dependent hydrolase	218
638191427	268	40.79	1	265	3	279	1.0e-80	293	COG0077	Prephenate dehydratase	279
638191428	314	15.12	4	284	3	291	9.0e-06	44.7	COG0463	Glycosyltransferases involved in cell wall biogenesis	291
638191429	377	18.37	1	368	1	377	9.0e-17	81.6	COG0438	Glycosyltransferase	381
638191430	367	18.44	16	367	1	378	2.0e-10	60.4	COG0438	Glycosyltransferase	381
638191433	178	27.27	1	154	93	231	7.0e-07	47.3	COG2801	Transposase and inactivated derivatives	232
638191434	205	27.96	24	205	30	210	4.0e-42	164	COG5421	Transposase	480
638191435	270	25.08	3	270	1	301	4.0e-31	128	COG1216	Predicted glycosyltransferases	305
638191436	248	31.6	21	247	107	333	2.0e-38	152	COG3328	Transposase and inactivated derivatives	379
638191442	396	19.44	13	395	2	381	1.0e-21	97.8	COG0438	Glycosyltransferase	381
638191445	251	25.26	71	237	79	256	1.0e-14	73.7	COG4974	Site-specific recombinase XerD	300
638191446	162	44.23	7	156	43	195	4.0e-42	163	COG0656	Aldo/keto reductases, related to diketogulonate reductase	280
638191449	376	17.93	45	376	26	375	4.0e-13	69.3	COG0438	Glycosyltransferase	381
638191450	102	17.33	16	88	1	75	5.0e-14	69.4	COG0361	Translation initiation factor 1 (IF-1)	75
638191453	353	22.19	13	351	11	375	8.0e-26	111	COG0438	Glycosyltransferase	381
638191454	223	37.78	93	137	120	163	1.0e-05	43.3	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
638191457	264	18.62	18	263	6	245	9.0e-08	50.9	COG0463	Glycosyltransferases involved in cell wall biogenesis	291
638191459	544	35.83	1	460	2	458	5.0e-94	338	COG3463	Predicted membrane protein	458
638191460	307	32.58	6	304	1	308	1.0e-46	180	COG0451	Nucleoside-diphosphate-sugar epimerases	314
638191461	324	52.1	1	322	1	333	1.0e-121	429	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
638191462	506	23.93	1	486	1	480	9.0e-19	88.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
638191463	581	29.73	1	581	4	618	6.0e-91	328	COG1506	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases	620
638191464	341	16.36	1	304	4	332	3.0e-08	53.1	COG0438	Glycosyltransferase	381
638191467	340	22.07	1	201	53	261	2.0e-06	46.9	COG1215	Glycosyltransferases, probably involved in cell wall biogenesis	439
638191468	160	34.55	100	154	162	216	1.0e-06	46.4	COG2264	Ribosomal protein L11 methylase	300
638191469	505	32.65	3	505	9	539	0.0e+00	479	COG0405	Gamma-glutamyltransferase	539
638191470	409	23.33	7	400	19	448	2.0e-16	80.2	COG2271	Sugar phosphate permease	448
638191471	1030	51.71	1	636	39	668	0.0e+00	922	COG4946	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system	668
638191472	245	31.82	38	143	53	162	1.0e-16	79.9	COG2226	Methylase involved in ubiquinone/menaquinone biosynthesis	238
638191474	475	20.77	21	460	19	458	2.0e-18	87.5	COG0531	Amino acid transporters	466
638191475	351	43.2	3	295	1	286	1.0e-98	353	COG1209	dTDP-glucose pyrophosphorylase	286
638191476	280	33.57	3	275	2	281	7.0e-72	264	COG1091	dTDP-4-dehydrorhamnose reductase	281
638191477	179	54.86	3	173	1	173	2.0e-54	205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes	173
638191478	318	54.23	1	311	1	318	0.0e+00	468	COG1088	dTDP-D-glucose 4,6-dehydratase	340
638191479	127	34.57	9	89	267	342	8.0e-11	59.3	COG0675	Transposase and inactivated derivatives	364
638191480	325	20.79	1	268	1	276	2.0e-06	47.1	COG0463	Glycosyltransferases involved in cell wall biogenesis	291
638191481	256	29.26	1	253	1	310	1.0e-28	120	COG0451	Nucleoside-diphosphate-sugar epimerases	314
638191484	217	22.12	1	217	4	213	2.0e-31	129	COG3413	Predicted DNA binding protein	215
638191486	455	18.07	48	374	35	314	2.0e-09	57.5	COG2814	Arabinose efflux permease	394
638191487	372	33.68	1	372	11	396	1.0e-105	376	COG1804	Predicted acyl-CoA transferases/carnitine dehydratase	396
638191488	344	29.66	1	344	4	379	3.0e-64	239	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
638191490	295	21.03	8	293	1	281	2.0e-24	106	COG0596	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)	282
638191491	466	23.54	1	463	5	465	2.0e-26	113	COG0531	Amino acid transporters	466
638191493	592	31.05	1	592	1	619	2.0e-104	373	COG1506	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases	620
638191495	457	31.81	1	454	8	530	7.0e-101	361	COG1574	Predicted metal-dependent hydrolase with the TIM-barrel fold	535
638191497	249	30.04	4	249	4	256	1.0e-40	160	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638191498	574	39.27	357	574	2	210	2.0e-57	217	COG2241	Precorrin-6B methylase 1	210
638191498	574	27.63	19	348	1	298	1.0e-49	191	COG2073	Cobalamin biosynthesis protein CbiG	298
638191501	254	58.8	2	251	3	252	1.0e-104	372	COG2875	Precorrin-4 methylase	254
638191502	233	36.75	5	233	2	230	5.0e-64	237	COG2243	Precorrin-2 methylase	234
638191503	201	42.55	15	201	5	187	1.0e-50	193	COG2242	Precorrin-6B methylase 2	187
638191504	378	43.09	11	376	7	367	4.0e-102	365	COG1903	Cobalamin biosynthesis protein CbiD	367
638191505	250	51	1	248	2	249	8.0e-96	343	COG1010	Precorrin-3B methylase	249
638191506	237	45.15	33	237	3	208	1.0e-61	229	COG2082	Precorrin isomerase	210
638191507	252	32.91	1	232	3	235	6.0e-53	201	COG0007	Uroporphyrinogen-III methylase	244
638191508	214	28.64	1	211	4	210	3.0e-39	155	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
638191513	396	48.51	1	393	4	402	0.0e+00	492	COG0137	Argininosuccinate synthase	403
638191514	437	28.51	2	437	4	455	1.0e-112	399	COG0165	Argininosuccinate lyase	459
638191515	282	37.97	1	279	14	307	5.0e-65	241	COG3386	Gluconolactonase	307
638191516	312	22.84	19	243	25	234	6.0e-21	94.9	COG0491	Zn-dependent hydrolases, including glyoxylases	252
638191517	426	57.67	1	426	1	429	0.0e+00	671	COG1350	Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)	432
638191518	606	55.22	36	559	1	512	0.0e+00	748	COG1964	Predicted Fe-S oxidoreductases	514
638191519	133	38.69	1	133	1	137	7.0e-31	126	COG1371	Uncharacterized conserved protein	137
638191520	151	40	6	82	2	86	8.0e-16	76.4	COG1695	Predicted transcriptional regulators	138
638191521	329	40.52	1	306	2	292	2.0e-73	269	COG1131	ABC-type multidrug transport system, ATPase component	293
638191523	382	16.01	83	372	147	451	5.0e-23	102	COG1032	Fe-S oxidoreductase	490
638191524	219	37.91	4	155	1	152	1.0e-34	139	COG1321	Mn-dependent transcriptional regulator	154
638191525	497	21.14	56	495	43	465	9.0e-21	95.2	COG0531	Amino acid transporters	466
638191526	96	40.21	1	96	2	97	4.0e-20	89.5	COG0011	Uncharacterized conserved protein	100
638191528	207	29.36	2	199	1	218	5.0e-34	137	COG0637	Predicted phosphatase/phosphohexomutase	221
638191529	261	39.36	1	240	4	252	1.0e-55	209	COG0476	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	254
638191530	335	44.38	1	335	4	337	3.0e-100	358	COG1064	Zn-dependent alcohol dehydrogenases	339
638191531	132	33.58	1	132	1	134	3.0e-26	110	COG1321	Mn-dependent transcriptional regulator	154
638191533	745	60.27	207	715	1	490	0.0e+00	500	COG0464	ATPases of the AAA+ class	494
638191535	189	45.62	26	182	2	161	3.0e-32	131	COG3430	Uncharacterized protein conserved in archaea	161
638191536	253	26.88	1	245	8	286	7.0e-56	210	COG1184	Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family	301
638191537	270	26.26	1	270	11	307	7.0e-48	184	COG2017	Galactose mutarotase and related enzymes	308
638191539	386	22.55	34	360	43	354	3.0e-21	96.3	COG0675	Transposase and inactivated derivatives	364
638191541	376	19.59	8	376	54	436	3.0e-32	132	COG1215	Glycosyltransferases, probably involved in cell wall biogenesis	439
638191542	271	37.75	23	266	8	256	7.0e-76	277	COG2519	tRNA(1-methyladenosine) methyltransferase and related methyltransferases	256
638191543	196	47.16	12	185	1	176	3.0e-57	214	COG0279	Phosphoheptose isomerase	176
638191546	295	35.81	1	292	2	293	5.0e-62	231	COG1131	ABC-type multidrug transport system, ATPase component	293
638191547	303	31.8	1	291	1	324	5.0e-63	234	COG1052	Lactate dehydrogenase and related dehydrogenases	324
638191549	315	33.57	173	308	1	139	9.0e-25	107	COG2246	Predicted membrane protein	139
638191550	695	42.3	7	534	1	530	0.0e+00	473	COG5650	Predicted integral membrane protein	536
638191551	637	46.3	168	635	69	536	3.0e-113	402	COG5650	Predicted integral membrane protein	536
638191552	365	21.54	96	341	1	192	1.0e-13	71.2	COG2391	Predicted transporter component	198
638191553	301	24.91	4	261	1	240	9.0e-22	97.8	COG0704	Phosphate uptake regulator	240
638191554	249	28.98	1	244	5	248	3.0e-13	68.9	COG0730	Predicted permeases	258
638191559	385	44.94	1	380	1	405	0.0e+00	490	COG4198	Uncharacterized conserved protein	405
638191560	280	41.07	11	280	1	277	1.0e-73	269	COG0648	Endonuclease IV	280
638191561	237	34.75	7	224	1	234	1.0e-40	160	COG1378	Predicted transcriptional regulators	247
638191562	393	30.23	12	393	1	390	5.0e-76	278	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
638191563	250	20.51	4	250	3	274	5.0e-28	118	COG0388	Predicted amidohydrolase	274
638191564	234	22.99	19	231	19	277	5.0e-21	94.8	COG0596	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)	282
638191565	886	29.92	6	874	3	740	0.0e+00	630	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
638191566	138	32.86	1	138	3	141	7.0e-38	149	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
638191567	114	27.35	1	114	2	106	8.0e-16	75.8	COG2146	Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	106
638191568	289	20.35	4	253	2	284	3.0e-26	112	COG0524	Sugar kinases, ribokinase family	311
638191569	173	47.4	1	173	3	175	1.0e-51	195	COG0663	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily	176
638191570	401	45.83	4	399	3	408	0.0e+00	475	COG0148	Enolase	423
638191571	206	39.15	1	206	1	212	8.0e-70	256	COG1798	Diphthamide biosynthesis methyltransferase	260
638191572	179	42.93	1	179	23	217	3.0e-32	131	COG1777	Predicted transcriptional regulators	217
638191573	183	24.68	46	183	1	146	1.0e-13	69.6	COG0071	Molecular chaperone (small heat shock protein)	146
638191574	1015	21.69	9	1010	6	924	0.0e+00	507	COG2409	Predicted drug exporters of the RND superfamily	937
638191575	410	58.77	6	410	16	420	0.0e+00	617	COG0499	S-adenosylhomocysteine hydrolase	420
638191576	441	46.86	1	441	1	428	0.0e+00	522	COG0172	Seryl-tRNA synthetase	429
638191577	348	24.6	166	348	49	222	5.0e-13	69.1	COG0569	K+ transport systems, NAD-binding component	225
638191579	331	21.73	1	328	5	360	8.0e-63	234	COG0162	Tyrosyl-tRNA synthetase	401
638191581	262	35.74	11	256	11	248	7.0e-55	207	COG0095	Lipoate-protein ligase A	248
638191582	455	45.96	2	441	1	441	0.0e+00	501	COG0541	Signal recognition particle GTPase	451
638191583	396	35.07	1	396	1	386	6.0e-68	251	COG0644	Dehydrogenases (flavoproteins)	396
638191584	70	47.37	8	64	165	221	7.0e-09	52.2	COG2221	Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits	317
638191586	429	48.39	1	429	2	435	0.0e+00	543	COG0017	Aspartyl/asparaginyl-tRNA synthetases	435
638191587	234	42.13	1	234	12	244	5.0e-59	221	COG1836	Predicted membrane protein	247
638191588	336	62.46	5	336	1	296	0.0e+00	461	COG0214	Pyridoxine biosynthesis enzyme	296
638191589	448	43.28	6	441	1	438	0.0e+00	499	COG0015	Adenylosuccinate lyase	438
638191591	205	42.72	1	204	7	219	3.0e-58	218	COG2102	Predicted ATPases of PP-loop superfamily	223
638191593	326	32.81	3	316	2	317	6.0e-72	264	COG0611	Thiamine monophosphate kinase	317
638191594	493	23.87	2	490	9	491	1.0e-65	244	COG0608	Single-stranded DNA-specific exonuclease	491
638191595	350	50.99	1	342	7	358	4.0e-122	431	COG1244	Predicted Fe-S oxidoreductase	358
638191596	381	42.46	4	380	1	391	3.0e-114	405	COG0436	Aspartate/tyrosine/aromatic aminotransferase	393
638191597	309	37.99	4	305	2	299	2.0e-75	276	COG0083	Homoserine kinase	299
638191598	368	38.48	3	368	15	396	5.0e-108	384	COG0626	Cystathionine beta-lyases/cystathionine gamma-synthases	396
638191600	142	32.09	10	142	2	135	8.0e-31	126	COG3439	Uncharacterized conserved protein	137
638191601	382	31.16	1	380	1	372	3.0e-88	319	COG0012	Predicted GTPase, probable translation factor	372
638191602	540	23.25	33	507	1	488	7.0e-62	231	COG1032	Fe-S oxidoreductase	490
638191603	308	26.18	2	307	5	299	9.0e-32	131	COG0501	Zn-dependent protease with chaperone function	302
638191604	425	30.23	71	378	1	311	9.0e-58	217	COG0630	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	312
638191605	279	19.71	1	276	29	307	3.0e-13	69.5	COG2064	Flp pilus assembly protein TadC	320
638191606	245	22.18	10	245	54	310	2.0e-06	46.4	COG2064	Flp pilus assembly protein TadC	320
638191607	410	36.57	44	347	1	309	2.0e-69	256	COG0630	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	312
638191608	420	23.6	1	417	11	419	1.0e-38	154	COG0025	NhaP-type Na+/H+ and K+/H+ antiporters	429
638191609	242	43.02	1	242	2	259	1.0e-73	269	COG0171	NAD synthase	268
638191610	281	42.76	4	278	1	283	1.0e-84	306	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
638191611	361	20.54	4	360	1	350	1.0e-46	180	COG1063	Threonine dehydrogenase and related Zn-dependent dehydrogenases	350
638191612	541	37.42	1	450	5	477	0.0e+00	465	COG0469	Pyruvate kinase	477
638191613	493	41.34	4	478	2	470	0.0e+00	484	COG1012	NAD-dependent aldehyde dehydrogenases	472
638191614	237	31.23	3	233	1	251	2.0e-50	192	COG0134	Indole-3-glycerol phosphate synthase	254
638191615	183	45.83	1	183	2	190	8.0e-60	223	COG0512	Anthranilate/para-aminobenzoate synthases component II	191
638191616	351	36.41	1	351	74	451	4.0e-84	305	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
638191617	195	36.23	1	190	2	208	3.0e-39	155	COG0135	Phosphoribosylanthranilate isomerase	208
638191618	330	36.86	4	326	8	338	5.0e-88	318	COG0547	Anthranilate phosphoribosyltransferase	338
638191619	237	25.5	1	236	17	262	5.0e-46	177	COG0159	Tryptophan synthase alpha chain	265
638191621	127	40.46	1	127	3	132	2.0e-36	144	COG1833	Uncharacterized conserved protein	132
638191622	223	37.34	1	223	6	238	2.0e-60	225	COG2226	Methylase involved in ubiquinone/menaquinone biosynthesis	238
638191623	100	57.58	2	100	3	101	3.0e-35	139	COG2412	Uncharacterized conserved protein	101
638191624	699	46.35	15	698	3	682	0.0e+00	682	COG1241	Predicted ATPase involved in replication control, Cdc46/Mcm family	682
638191626	272	37.72	1	270	1	281	1.0e-60	226	COG0061	Predicted sugar kinase	281
638191627	122	28.12	1	120	1	128	6.0e-20	89.4	COG1310	Predicted metal-dependent protease of the PAD1/JAB1 superfamily	134
638191629	578	30.54	31	490	3	438	2.0e-35	144	COG0531	Amino acid transporters	466
638191630	482	36.03	101	476	1	334	2.0e-90	326	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
638191632	306	38.51	6	296	5	293	3.0e-62	232	COG1131	ABC-type multidrug transport system, ATPase component	293
638191634	76	61.54	25	76	1	52	2.0e-14	70.7	COG3466	Putative transposon-encoded protein	52
638191635	435	28.83	2	434	1	400	1.0e-76	280	COG0004	Ammonia permease	409
638191639	442	21.25	40	433	48	434	1.0e-14	74.5	COG2271	Sugar phosphate permease	448
638191640	369	31.1	1	367	1	366	2.0e-65	243	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
638191641	619	23.16	1	616	14	792	1.0e-86	314	COG0417	DNA polymerase elongation subunit (family B)	792
638191644	256	24.44	2	256	50	318	2.0e-26	113	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638191645	732	33.87	18	719	7	697	0.0e+00	621	COG0480	Translation elongation factors (GTPases)	697
638191646	104	47.62	1	104	1	104	2.0e-33	134	COG0051	Ribosomal protein S10	104
638191647	427	65.81	4	426	1	428	0.0e+00	641	COG5256	Translation elongation factor EF-1alpha (GTPase)	428
638191648	326	40.06	3	312	2	313	3.0e-91	328	COG2896	Molybdenum cofactor biosynthesis enzyme	322
638191650	514	37.58	25	501	5	470	5.0e-116	411	COG1012	NAD-dependent aldehyde dehydrogenases	472
638191652	387	50	2	322	1	322	3.0e-97	349	COG0003	Oxyanion-translocating ATPase	322
638191653	326	37.96	6	322	2	321	3.0e-72	265	COG0142	Geranylgeranyl pyrophosphate synthase	322
638191654	89	63.33	1	89	1	90	2.0e-27	113	COG1581	Archaeal DNA-binding protein	91
638191655	233	24.9	1	230	3	249	2.0e-18	85.7	COG1028	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	251
638191656	391	15.77	19	350	23	350	6.0e-06	45.6	COG2814	Arabinose efflux permease	394
638191659	256	26.07	18	255	68	324	1.0e-25	110	COG0592	DNA polymerase sliding clamp subunit (PCNA homolog)	364
638191661	426	22.88	1	420	9	416	2.0e-66	246	COG1721	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	416
638191662	319	44.21	1	314	2	328	4.0e-70	258	COG0714	MoxR-like ATPases	329
638191666	555	45.75	46	555	1	515	0.0e+00	594	COG1549	Queuine tRNA-ribosyltransferases, contain PUA domain	519
638191667	246	25.86	5	233	4	266	2.0e-45	176	COG0101	Pseudouridylate synthase	266
638191668	338	20.39	168	338	17	222	1.0e-17	84	COG1418	Predicted HD superfamily hydrolase	222
638191668	338	62.71	1	173	3	179	2.0e-72	266	COG1303	Uncharacterized protein conserved in archaea	179
638191669	168	74.71	1	168	1	169	7.0e-69	253	COG4860	Uncharacterized protein conserved in archaea	170
638191672	334	33.33	2	331	1	341	9.0e-74	270	COG2520	Predicted methyltransferase	341
638191673	71	46.67	1	70	5	79	4.0e-11	60	COG1958	Small nuclear ribonucleoprotein (snRNP) homolog	79
638191675	202	45.74	1	184	1	188	4.0e-58	217	COG1096	Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)	188
638191676	384	18.49	23	374	30	383	1.0e-11	64.8	COG2814	Arabinose efflux permease	394
638191677	397	29.88	6	395	9	403	8.0e-70	257	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases	409
638191679	462	32.93	1	462	11	499	8.0e-128	450	COG0442	Prolyl-tRNA synthetase	500
638191680	212	23.83	3	212	2	212	2.0e-32	132	COG0560	Phosphoserine phosphatase	212
638191683	312	60.74	14	311	2	284	9.0e-102	363	COG1405	Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB	285
638191684	68	34.67	1	68	2	76	4.0e-11	59.9	COG3277	RNA-binding protein involved in rRNA processing	98
638191685	325	46.2	1	325	2	330	3.0e-112	398	COG1084	Predicted GTPase	346
638191686	548	36	86	534	1	469	4.0e-105	375	COG0008	Glutamyl- and glutaminyl-tRNA synthetases	472
638191687	84	40.96	4	84	3	85	2.0e-14	70.3	COG1873	Uncharacterized conserved protein	87
638191688	202	38.19	3	192	2	198	7.0e-45	173	COG0518	GMP synthase - Glutamine amidotransferase domain	198
638191689	313	53.72	16	311	3	283	1.0e-95	343	COG1405	Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB	285
638191690	428	42.56	1	428	2	435	0.0e+00	507	COG0017	Aspartyl/asparaginyl-tRNA synthetases	435
638191691	314	44.16	1	314	1	283	1.0e-81	296	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638191693	143	42.36	1	143	4	139	1.0e-35	142	COG1813	Predicted transcription factor, homolog of eukaryotic MBF1	165
638191694	279	43.61	58	279	3	229	1.0e-83	303	COG1889	Fibrillarin-like rRNA methylase	231
638191695	159	36.89	5	123	2	116	3.0e-24	104	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
638191696	241	56.39	1	224	1	222	5.0e-80	290	COG0603	Predicted PP-loop superfamily ATPase	222
638191697	325	40.56	4	322	1	313	2.0e-94	339	COG0039	Malate/lactate dehydrogenases	313
638191698	475	18.96	1	264	2	260	1.0e-21	97.9	COG0467	RecA-superfamily ATPases implicated in signal transduction	260
638191699	203	50.52	1	188	1	194	6.0e-71	260	COG0450	Peroxiredoxin	194
638191700	321	55.21	1	321	4	329	0.0e+00	470	COG0113	Delta-aminolevulinic acid dehydratase	330
638191704	473	34.91	1	473	2	475	5.0e-84	305	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
638191705	516	37.72	1	505	8	497	2.0e-110	392	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
638191706	335	37.88	1	328	291	606	3.0e-56	212	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
638191707	332	46.44	6	325	2	317	1.0e-75	277	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
638191708	103	42.72	1	103	2	100	7.0e-18	82.1	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
638191711	143	38.64	12	143	12	143	6.0e-36	143	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
638191712	346	38.3	11	346	1	332	9.0e-79	287	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
638191713	369	53.96	3	369	8	398	0.0e+00	537	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit 7	398
638191714	151	41.78	12	151	28	173	1.0e-39	155	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit	176
638191715	157	62.42	8	156	18	165	7.0e-65	239	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases	194
638191716	144	34.72	1	144	4	122	2.0e-22	98.3	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
638191717	598	46.53	1	598	6	622	0.0e+00	736	COG2511	Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain)	631
638191718	406	33.24	30	393	1	351	7.0e-86	311	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
638191719	257	33.46	1	257	2	254	9.0e-59	220	COG1801	Uncharacterized conserved protein	263
638191720	384	46.17	3	384	2	393	1.0e-100	360	COG1960	Acyl-CoA dehydrogenases	393
638191721	333	40.12	2	332	4	340	9.0e-85	307	COG1467	Eukaryotic-type DNA primase, catalytic (small) subunit	341
638191722	1097	40.7	1	1093	28	1174	0.0e+00	803	COG4934	Predicted protease	1174
638191723	347	32.77	3	345	1	330	4.0e-72	265	COG0620	Methionine synthase II (cobalamin-independent)	330
638191724	293	22.36	1	293	3	325	5.0e-38	151	COG0620	Methionine synthase II (cobalamin-independent)	330
638191725	263	29.82	1	263	5	287	8.0e-45	174	COG0685	5,10-methylenetetrahydrofolate reductase	291
638191727	130	31.88	2	130	7	144	1.0e-14	72.4	COG1522	Transcriptional regulators	154
638191728	549	47.18	16	536	1	524	0.0e+00	502	COG0459	Chaperonin GroEL (HSP60 family)	524
638191729	326	44.09	20	326	1	305	3.0e-75	275	COG0492	Thioredoxin reductase	305
638191732	222	38.05	1	222	1	226	2.0e-56	211	COG1171	Threonine dehydratase	347
638191733	105	25.97	1	77	284	349	6.0e-09	52.4	COG0675	Transposase and inactivated derivatives	364
638191734	288	40.62	1	288	14	299	2.0e-74	272	COG0109	Polyprenyltransferase (cytochrome oxidase assembly factor)	304
638191736	151	48.36	30	151	1	122	7.0e-39	153	COG1727	Ribosomal protein L18E	122
638191737	136	34.11	1	113	15	142	8.0e-24	102	COG0102	Ribosomal protein L13	148
638191738	132	45.86	1	132	3	130	3.0e-33	134	COG0103	Ribosomal protein S9	130
638191739	72	51.39	1	72	1	63	4.0e-20	89.5	COG1644	DNA-directed RNA polymerase, subunit N (RpoN/RPB10)	63
638191743	279	41.83	17	273	4	266	8.0e-69	253	COG0345	Pyrroline-5-carboxylate reductase	266
638191745	498	38.37	7	498	2	499	0.0e+00	534	COG0554	Glycerol kinase	499
638191747	440	23.88	1	436	1	432	5.0e-37	149	COG1653	ABC-type sugar transport system, periplasmic component	433
638191748	309	31.63	18	309	1	292	5.0e-50	191	COG1175	ABC-type sugar transport systems, permease components	295
638191749	295	41.84	14	290	3	278	4.0e-55	208	COG0395	ABC-type sugar transport system, permease component	281
638191750	371	46.72	1	351	2	338	7.0e-111	394	COG3839	ABC-type sugar transport systems, ATPase components	338
638191751	643	32.42	1	631	3	641	0.0e+00	481	COG3408	Glycogen debranching enzyme	641
638191752	585	26.18	6	582	14	641	8.0e-103	368	COG3408	Glycogen debranching enzyme	641
638191753	352	30.83	11	259	1	247	2.0e-45	176	COG1378	Predicted transcriptional regulators	247
638191754	650	43.59	64	625	1	528	0.0e+00	647	COG0365	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases	528
638191755	203	50	4	196	10	207	4.0e-50	190	COG1584	Predicted membrane protein	207
638191756	288	38.73	8	287	2	263	6.0e-72	264	COG0656	Aldo/keto reductases, related to diketogulonate reductase	280
638191759	327	28.26	11	285	7	255	3.0e-14	72.7	COG0730	Predicted permeases	258
638191760	126	71.07	6	126	5	125	6.0e-32	129	COG4272	Predicted membrane protein	125
638191761	484	38	24	456	8	457	4.0e-110	391	COG0493	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	457
638191762	406	58.82	2	400	1	408	0.0e+00	557	COG3635	Predicted phosphoglycerate mutase, AP superfamily	408
638191764	461	18.77	85	406	63	354	3.0e-06	46.7	COG2814	Arabinose efflux permease	394
638191765	399	46.46	1	394	4	396	0.0e+00	472	COG1804	Predicted acyl-CoA transferases/carnitine dehydratase	396
638191766	143	37.37	43	140	28	126	6.0e-10	56.9	COG1846	Transcriptional regulators	126
638191767	587	15.98	52	369	52	384	2.0e-07	51.4	COG2814	Arabinose efflux permease	394
638191770	190	59.55	16	190	1	175	3.0e-59	221	COG4741	Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase	175
638191771	201	28.12	11	166	4	163	2.0e-16	79	COG0596	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)	282
638191772	419	41.86	1	417	11	436	3.0e-120	425	COG1257	Hydroxymethylglutaryl-CoA reductase	436
638191774	301	42.12	3	301	1	310	3.0e-85	308	COG0167	Dihydroorotate dehydrogenase	310
638191775	250	29.44	4	229	10	252	4.0e-45	175	COG0543	2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	252
638191780	397	34.58	3	394	1	390	2.0e-72	266	COG1960	Acyl-CoA dehydrogenases	393
638191781	182	47.03	1	182	7	191	7.0e-51	193	COG1094	Predicted RNA-binding protein (contains KH domains)	194
638191783	251	43.35	1	251	2	264	2.0e-79	289	COG1718	Serine/threonine protein kinase involved in cell cycle control	268
638191784	123	37.5	35	105	4	75	2.0e-18	84.8	COG0361	Translation initiation factor 1 (IF-1)	75
638191785	142	22.22	1	141	41	183	2.0e-17	81.4	COG0195	Transcription elongation factor	190
638191786	508	28.49	4	508	280	752	7.0e-79	288	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
638191787	886	35.05	7	871	3	797	0.0e+00	832	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
638191788	1195	33.03	2	1195	15	1060	0.0e+00	1096	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
638191789	87	62.2	1	82	4	80	1.0e-23	101	COG2012	DNA-directed RNA polymerase, subunit H, RpoH/RPB5	80
638191791	271	46.5	1	192	3	196	2.0e-54	206	COG3390	Uncharacterized protein conserved in archaea	196
638191792	363	26.54	1	363	43	407	6.0e-58	218	COG1599	Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	407
638191793	232	30.93	136	232	1	95	9.0e-19	87.2	COG3432	Predicted transcriptional regulator	95
638191794	393	20.05	1	367	1	354	5.0e-22	99	COG0675	Transposase and inactivated derivatives	364
638191795	107	35.05	1	97	1	95	2.0e-18	84.5	COG3432	Predicted transcriptional regulator	95
638191796	169	46.79	10	165	12	165	3.0e-46	178	COG0221	Inorganic pyrophosphatase	171
638191798	196	41.62	1	196	23	198	6.0e-58	217	COG2109	ATP:corrinoid adenosyltransferase	198
638191799	222	50.22	1	222	2	223	6.0e-71	260	COG1756	Uncharacterized conserved protein	223
638191803	388	31.4	1	368	1	367	8.0e-77	281	COG4948	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	372
638191804	229	24.04	1	202	2	166	9.0e-14	70.8	COG0622	Predicted phosphoesterase	172
638191805	129	25	1	129	16	147	1.0e-12	65.9	COG1522	Transcriptional regulators	154
638191806	513	24.72	1	510	2	532	2.0e-98	353	COG0028	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]	550
638191807	304	35.79	10	302	16	314	9.0e-78	283	COG0111	Phosphoglycerate dehydrogenase and related dehydrogenases	324
638191808	156	47.62	1	146	1	143	2.0e-59	221	COG4275	Uncharacterized conserved protein	143
638191809	862	35.8	2	859	1	768	0.0e+00	673	COG2366	Protein related to penicillin acylase	768
638191811	107	50	1	107	9	117	2.0e-29	120	COG3462	Predicted membrane protein	117
638191812	167	31.4	1	165	87	258	7.0e-25	106	COG2512	Uncharacterized membrane-associated protein/domain	258
638191813	513	21.79	22	193	46	217	5.0e-10	59.6	COG3063	Tfp pilus assembly protein PilF	250
638191814	263	57.36	1	262	3	266	9.0e-112	396	COG3375	Uncharacterized conserved protein	266
638191815	411	23.58	2	407	1	393	1.0e-34	141	COG1252	NADH dehydrogenase, FAD-containing subunit	405
638191818	145	30.69	43	143	1	85	1.0e-16	79.4	COG0184	Ribosomal protein S15P/S13E	89
638191819	443	23.63	1	436	14	485	4.0e-49	189	COG0608	Single-stranded DNA-specific exonuclease	491
638191822	2076	26.7	7	858	1	768	1.0e-102	369	COG1287	Uncharacterized membrane protein, required for N-linked glycosylation	773
638191824	124	40	3	122	1	119	5.0e-16	76.4	COG1382	Prefoldin, chaperonin cofactor	119
638191825	284	38.62	2	280	3	289	1.0e-81	296	COG1469	Uncharacterized conserved protein	289
638191826	142	45.71	1	137	1	140	1.0e-35	142	COG0615	Cytidylyltransferase	140
638191827	150	28.92	1	150	12	177	3.0e-16	77.7	COG0456	Acetyltransferases	177
638191828	157	37.96	11	143	2	138	6.0e-35	140	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	138
638191829	198	53.4	1	198	1	203	3.0e-72	264	COG0856	Orotate phosphoribosyltransferase homologs	203
638191830	503	47.12	1	499	2	521	0.0e+00	614	COG1384	Lysyl-tRNA synthetase (class I)	521
638191831	543	44.55	5	542	6	550	0.0e+00	622	COG0143	Methionyl-tRNA synthetase	558
638191834	486	18.16	1	468	2	460	3.0e-20	93.7	COG0531	Amino acid transporters	466
638191835	416	19.31	12	388	8	349	8.0e-29	121	COG0675	Transposase and inactivated derivatives	364
638191836	191	36.13	1	191	2	188	4.0e-51	194	COG2452	Predicted site-specific integrase-resolvase	193
638191837	61	32.79	1	61	12	72	3.0e-09	53.4	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
638191838	145	50	1	145	2	145	3.0e-45	173	COG1860	Uncharacterized protein conserved in archaea	147
638191839	366	42.18	19	366	1	357	5.0e-106	378	COG0371	Glycerol dehydrogenase and related enzymes	360
638191840	289	34.72	1	284	4	289	7.0e-72	264	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
638191842	311	37.67	11	308	1	292	9.0e-78	283	COG1234	Metal-dependent hydrolases of the beta-lactamase superfamily III	292
638191844	268	37.68	1	268	1	263	4.0e-68	251	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
638191845	693	43.02	1	624	2	598	0.0e+00	590	COG1042	Acyl-CoA synthetase (NDP forming)	598
638191847	119	33.33	2	118	1	120	1.0e-22	98.9	COG1658	Small primase-like proteins (Toprim domain)	127
638191848	145	38.61	1	145	46	203	8.0e-19	86.3	COG1599	Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	407
638191849	588	35.87	65	577	1	444	9.0e-107	381	COG1793	ATP-dependent DNA ligase	444
638191850	561	27.87	1	466	1	444	3.0e-32	133	COG0531	Amino acid transporters	466
638191851	624	39.39	1	620	1	614	0.0e+00	655	COG2414	Aldehyde:ferredoxin oxidoreductase	614
638191852	678	38.63	20	658	65	713	0.0e+00	607	COG2217	Cation transport ATPase	713
638191853	45	60.87	1	45	3	48	2.0e-12	64.2	COG3350	Uncharacterized conserved protein	53
638191854	64	61.02	4	62	1	59	1.0e-15	75	COG5466	Predicted small metal-binding protein	59
638191855	395	34.19	5	385	1	405	4.0e-80	292	COG1488	Nicotinic acid phosphoribosyltransferase	405
638191856	472	48.06	19	472	2	464	0.0e+00	574	COG0215	Cysteinyl-tRNA synthetase	464
638191858	154	24.19	24	147	3	126	1.0e-14	72.7	COG1846	Transcriptional regulators	126
638191860	215	43.46	1	214	1	214	4.0e-69	254	COG1890	Ribosomal protein S3AE	214
638191861	78	45.33	5	78	4	78	2.0e-15	73.8	COG0425	Predicted redox protein, regulator of disulfide bond formation	78
638191862	137	47.83	1	137	1	137	2.0e-36	144	COG2210	Uncharacterized conserved protein	137
638191863	193	40.61	1	193	1	195	5.0e-44	170	COG3374	Predicted membrane protein	197
638191865	340	53.53	15	333	7	346	0.0e+00	464	COG0182	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family	346
638191866	426	32.24	54	226	2	176	7.0e-44	171	COG0180	Tryptophanyl-tRNA synthetase	314
638191868	447	37.92	2	440	15	486	0.0e+00	486	COG0380	Trehalose-6-phosphate synthase	486
638191869	246	33.2	1	246	2	260	1.0e-57	216	COG1877	Trehalose-6-phosphatase	266
638191871	270	36.59	1	265	3	273	4.0e-53	201	COG0388	Predicted amidohydrolase	274
638191872	154	28.21	1	114	6	119	3.0e-11	61.2	COG1051	ADP-ribose pyrophosphatase	145
638191873	164	39.29	28	163	2	140	1.0e-34	139	COG1545	Predicted nucleic-acid-binding protein containing a Zn-ribbon	140
638191874	420	28.4	5	419	1	392	1.0e-70	260	COG0183	Acetyl-CoA acetyltransferase	392
638191876	518	26.06	9	446	9	447	2.0e-21	97.1	COG0531	Amino acid transporters	466
638191879	116	28.83	8	116	3	113	6.0e-11	59.5	COG1695	Predicted transcriptional regulators	138
638191880	641	40.29	66	611	1	524	0.0e+00	587	COG0365	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases	528
638191882	619	34.51	71	593	1	526	0.0e+00	485	COG0365	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases	528
638191883	382	37.18	1	376	2	391	2.0e-88	319	COG1960	Acyl-CoA dehydrogenases	393
638191884	186	32.29	1	183	1	192	2.0e-38	152	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
638191885	373	37.11	1	373	2	388	3.0e-96	345	COG1748	Saccharopine dehydrogenase and related proteins	389
638191886	117	38.83	10	108	1	100	9.0e-19	85.4	COG1733	Predicted transcriptional regulators	120
638191887	231	55.09	1	212	1	215	1.0e-74	272	COG2231	Uncharacterized protein related to Endonuclease III	215
638191888	411	64.82	2	411	1	415	0.0e+00	664	COG5257	Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)	415
638191889	128	52.5	1	118	1	120	3.0e-36	144	COG2125	Ribosomal protein S6E (S10)	120
638191890	527	46.63	2	325	2	342	2.0e-111	396	COG0533	Metal-dependent proteases with possible chaperone activity	342
638191890	527	46.39	336	527	7	200	6.0e-66	245	COG3642	Mn2+-dependent serine/threonine protein kinase	204
638191891	185	44.44	4	183	6	194	2.0e-52	198	COG0127	Xanthosine triphosphate pyrophosphatase	194
638191892	428	33.95	1	428	1	396	5.0e-70	258	COG0644	Dehydrogenases (flavoproteins)	396
638191893	90	49.46	1	90	7	99	1.0e-26	110	COG2440	Ferredoxin-like protein	99
638191894	265	42.64	2	256	1	252	5.0e-65	240	COG2086	Electron transfer flavoprotein, beta subunit	260
638191895	349	45.06	17	338	1	312	6.0e-99	354	COG2025	Electron transfer flavoprotein, alpha subunit	313
638191896	660	45.48	22	660	1	589	0.0e+00	667	COG0441	Threonyl-tRNA synthetase	589
638191897	436	36.7	1	436	15	468	2.0e-114	406	COG1012	NAD-dependent aldehyde dehydrogenases	472
638191898	433	36.84	14	431	1	377	2.0e-98	353	COG1454	Alcohol dehydrogenase, class IV	377
638191899	271	19.23	87	266	45	221	1.0e-08	54.1	COG0491	Zn-dependent hydrolases, including glyoxylases	252
638191902	223	25.61	12	223	4	249	2.0e-41	162	COG0149	Triosephosphate isomerase	251
638191903	170	50.6	3	163	1	164	1.0e-52	199	COG2131	Deoxycytidylate deaminase	164
638191906	294	30.82	2	291	5	247	9.0e-55	207	COG0152	Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	247
638191907	332	40.23	1	331	7	349	7.0e-97	347	COG0407	Uroporphyrinogen-III decarboxylase	352
638191908	304	32.39	1	287	4	320	2.0e-72	265	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
638191909	315	29.52	97	314	1	216	6.0e-25	108	COG0170	Dolichol kinase	216
638191911	100	48.39	5	97	2	90	7.0e-24	101	COG1849	Uncharacterized protein conserved in archaea	90
638191912	159	65.79	4	155	2	153	2.0e-59	221	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
638191913	361	45.75	2	211	1	211	1.0e-66	247	COG0009	Putative translation factor (SUA5)	211
638191914	783	33.21	2	783	21	856	0.0e+00	612	COG0308	Aminopeptidase N	859
638191915	507	23.56	5	502	1	492	6.0e-47	182	COG0591	Na+/proline symporter	493
638191917	791	34.66	31	791	1	764	0.0e+00	634	COG1501	Alpha-glucosidases, family 31 of glycosyl hydrolases	772
638191918	373	45.16	1	363	28	399	9.0e-101	360	COG0513	Superfamily II DNA and RNA helicases	513
638191919	396	38.21	4	395	2	391	6.0e-93	334	COG0183	Acetyl-CoA acetyltransferase	392
638191920	369	36.95	1	363	1	386	2.0e-81	295	COG1960	Acyl-CoA dehydrogenases	393
638191923	336	24.35	3	334	7	392	8.0e-38	151	COG1960	Acyl-CoA dehydrogenases	393
638191924	133	34.65	9	133	13	139	1.0e-21	95.5	COG2050	Uncharacterized protein, possibly involved in aromatic compounds catabolism	141
638191925	529	31.81	1	529	5	527	5.0e-110	391	COG0318	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II	534
638191926	659	43.73	2	323	2	306	2.0e-90	326	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638191926	659	38.46	401	656	1	257	8.0e-58	218	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638191927	114	32.41	8	114	16	122	9.0e-16	75.4	COG3255	Putative sterol carrier protein	134
638191928	174	36.13	1	117	1	116	2.0e-12	65.2	COG0517	FOG: CBS domain	117
638191929	558	19.96	32	547	1	490	2.0e-39	157	COG1032	Fe-S oxidoreductase	490
638191930	334	38.39	1	333	1	308	3.0e-80	292	COG0667	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)	316
638191931	613	37.38	9	608	5	612	0.0e+00	505	COG3387	Glucoamylase and related glycosyl hydrolases	612
638191932	360	37.02	3	356	1	360	4.0e-100	358	COG0337	3-dehydroquinate synthetase	360
638191933	267	35.79	1	254	1	270	2.0e-64	239	COG0169	Shikimate 5-dehydrogenase	283
638191934	268	39.64	2	268	1	278	2.0e-80	292	COG1685	Archaeal shikimate kinase	278
638191935	410	28.61	1	403	4	424	1.0e-89	323	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
638191936	545	35.33	1	545	1	577	4.0e-129	455	COG0018	Arginyl-tRNA synthetase	577
638191938	469	46.15	19	469	1	432	0.0e+00	532	COG1690	Uncharacterized conserved protein	432
638191940	109	69.31	7	107	1	101	4.0e-31	126	COG3388	Uncharacterized protein conserved in archaea	101
638191941	177	25	69	167	76	175	3.0e-11	61.5	COG1670	Acetyltransferases, including N-acetylases of ribosomal proteins	187
638191943	313	25.3	4	313	21	346	3.0e-34	139	COG0535	Predicted Fe-S oxidoreductases	347
638191945	477	49.16	3	358	1	309	9.0e-114	404	COG4608	ABC-type oligopeptide transport system, ATPase component	309
638191946	522	61.11	305	512	107	316	8.0e-84	304	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638191947	319	38.14	29	319	16	288	4.0e-53	202	COG1173	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components	289
638191948	363	36.87	6	363	4	315	2.0e-66	246	COG0601	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components	317
638191949	963	18.3	328	845	38	473	1.0e-13	72.8	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
638191951	285	44.01	8	284	7	287	5.0e-85	308	COG1013	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit	294
638191952	585	32.02	3	196	1	203	3.0e-30	127	COG1014	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit	203
638191952	585	33.59	200	579	1	365	4.0e-79	289	COG0674	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit	365
638191953	457	52.72	1	457	4	462	0.0e+00	676	COG1027	Aspartate ammonia-lyase	471
638191954	177	25.97	27	177	1	154	7.0e-21	93.6	COG1522	Transcriptional regulators	154
638191955	401	34.78	1	400	3	436	7.0e-102	364	COG0621	2-methylthioadenine synthetase	437
638191956	345	41.45	8	345	2	344	1.0e-99	356	COG1736	Diphthamide synthase subunit DPH2	347
638191959	500	28.65	36	223	8	191	1.0e-11	64.8	COG2814	Arabinose efflux permease	394
638191960	376	28.65	11	367	2	378	1.0e-58	220	COG1960	Acyl-CoA dehydrogenases	393
638191961	255	40.78	3	247	1	250	7.0e-52	197	COG1028	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	251
638191962	322	23.88	1	320	4	332	2.0e-43	169	COG0673	Predicted dehydrogenases and related proteins	342
638191963	361	27.49	1	358	4	372	2.0e-58	219	COG4948	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	372
638191965	120	30.97	1	112	11	123	1.0e-19	88.9	COG0599	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit	124
638191966	178	25	2	100	5	101	4.0e-09	54.6	COG1605	Chorismate mutase	101
638191967	197	21.78	1	197	27	244	1.0e-24	106	COG0287	Prephenate dehydrogenase	279
638191968	312	52.8	27	308	1	286	2.0e-112	399	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
638191969	367	42.8	60	320	1	260	8.0e-73	267	COG1180	Pyruvate-formate lyase-activating enzyme	260
638191970	495	50.81	1	493	3	498	0.0e+00	667	COG2986	Histidine ammonia-lyase	498
638191971	114	54.39	1	114	1	113	1.0e-34	138	COG3370	Uncharacterized protein conserved in archaea	113
638191974	468	22.27	1	464	4	465	8.0e-20	92.1	COG0531	Amino acid transporters	466
638191975	553	64.38	1	553	5	555	0.0e+00	905	COG2987	Urocanate hydratase	561
638191976	404	35.61	4	401	1	406	1.0e-90	327	COG1228	Imidazolonepropionase and related amidohydrolases	406
638191977	269	50.36	1	266	2	279	9.0e-96	343	COG1355	Predicted dioxygenase	279
638191978	201	49	4	201	1	200	4.0e-68	250	COG2078	Uncharacterized conserved protein	203
638191979	381	25.8	1	344	4	365	1.0e-58	220	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
638191980	310	48.1	4	310	1	313	2.0e-93	336	COG1619	Uncharacterized proteins, homologs of microcin C7 resistance protein MccF	313
638191984	449	22.77	48	445	36	394	5.0e-14	72.5	COG2814	Arabinose efflux permease	394
638191985	392	20.1	14	385	14	404	4.0e-10	59.5	COG2223	Nitrate/nitrite transporter	417
638191986	480	22.46	1	187	6	192	3.0e-13	70.2	COG2814	Arabinose efflux permease	394
638191987	305	41.06	5	304	4	291	9.0e-69	253	COG1131	ABC-type multidrug transport system, ATPase component	293
638191989	214	39.17	1	214	1	217	1.0e-67	249	COG1926	Predicted phosphoribosyltransferases	220
638191991	123	56.14	2	112	4	117	1.0e-39	155	COG3189	Uncharacterized conserved protein	117
638191994	466	47.12	2	462	20	481	0.0e+00	507	COG1311	Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B	481
638191996	395	21.93	5	387	18	439	3.0e-35	143	COG1012	NAD-dependent aldehyde dehydrogenases	472
638191997	485	28.84	255	469	1	169	2.0e-31	130	COG0516	IMP dehydrogenase/GMP reductase	170
638191997	485	37.17	96	204	177	289	4.0e-15	76.5	COG2524	Predicted transcriptional regulator, contains C-terminal CBS domains	294
638191998	249	39.84	1	248	5	252	2.0e-65	242	COG1427	Predicted periplasmic solute-binding protein	252
638191999	365	41.62	1	365	3	366	9.0e-102	363	COG1060	Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes	370
638192000	563	17.33	14	534	2	490	2.0e-45	177	COG1032	Fe-S oxidoreductase	490
638192001	366	43.8	6	366	7	367	6.0e-111	394	COG1060	Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes	370
638192002	409	42.13	12	398	24	399	3.0e-101	362	COG0585	Uncharacterized conserved protein	406
638192004	293	37.26	1	293	1	312	2.0e-73	268	COG2025	Electron transfer flavoprotein, alpha subunit	313
638192005	260	31.5	16	260	1	254	3.0e-52	198	COG2086	Electron transfer flavoprotein, beta subunit	260
638192008	450	34.71	1	446	2	454	2.0e-105	376	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	454
638192009	278	23.53	2	115	173	290	2.0e-08	53	COG2524	Predicted transcriptional regulator, contains C-terminal CBS domains	294
638192010	476	48.39	1	329	4	344	9.0e-125	440	COG0423	Glycyl-tRNA synthetase (class II)	558
638192011	404	28.04	9	398	4	406	2.0e-73	270	COG0719	ABC-type transport system involved in Fe-S cluster assembly, permease component	412
638192012	481	41.88	47	477	1	412	4.0e-118	418	COG0719	ABC-type transport system involved in Fe-S cluster assembly, permease component	412
638192013	246	57.49	1	246	2	247	2.0e-97	349	COG0396	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	251
638192014	215	32.41	1	215	3	213	1.0e-58	219	COG2345	Predicted transcriptional regulator	218
638192015	100	52.48	1	99	11	111	1.0e-28	117	COG2151	Predicted metal-sulfur cluster biosynthetic enzyme	111
638192016	184	63.04	1	184	2	185	8.0e-70	256	COG2101	TATA-box binding protein (TBP), component of TFIID and TFIIIB	185
638192017	659	31.3	288	657	1	385	7.0e-74	272	COG0247	Fe-S oxidoreductase	388
638192019	105	44.66	1	103	2	104	2.0e-34	136	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
638192020	196	20.36	24	178	20	181	2.0e-08	52.7	COG1670	Acetyltransferases, including N-acetylases of ribosomal proteins	187
638192021	189	33.33	13	154	54	203	2.0e-18	85.7	COG0666	FOG: Ankyrin repeat	235
638192022	265	30.26	2	265	11	275	1.0e-41	163	COG0863	DNA modification methylase	302
638192023	147	26.24	9	145	5	143	7.0e-28	116	COG1764	Predicted redox protein, regulator of disulfide bond formation	143
638192024	196	27.97	7	124	12	123	2.0e-14	72.4	COG0596	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)	282
638192025	370	41.55	4	369	1	414	1.0e-87	316	COG1078	HD superfamily phosphohydrolases	421
638192026	197	25.19	36	168	45	177	6.0e-12	64.1	COG2226	Methylase involved in ubiquinone/menaquinone biosynthesis	238
638192027	222	41.52	4	222	5	223	1.0e-51	196	COG2013	Uncharacterized conserved protein	227
638192029	247	37.94	1	245	1	251	2.0e-44	173	COG1028	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	251
638192033	337	15.18	45	227	1	191	5.0e-24	105	COG3039	Transposase and inactivated derivatives, IS5 family	230
638192036	316	20.5	1	309	6	300	5.0e-20	92.3	COG0863	DNA modification methylase	302
638192040	382	38.33	1	59	181	238	6.0e-06	45.7	COG1041	Predicted DNA modification methylase	347
638192048	313	23.81	23	139	81	201	3.0e-06	46.5	COG2382	Enterochelin esterase and related enzymes	299
638192049	160	28.12	1	159	1	156	2.0e-26	112	COG1547	Uncharacterized conserved protein	156
638192050	205	39.9	1	205	10	217	2.0e-60	225	COG2345	Predicted transcriptional regulator	218
638192051	474	19.04	10	460	1	444	5.0e-18	86.4	COG0531	Amino acid transporters	466
638192052	928	17.1	290	901	31	535	2.0e-20	95.4	COG0747	ABC-type dipeptide transport system, periplasmic component	556
638192053	459	17.96	33	402	36	363	9.0e-16	78.7	COG2814	Arabinose efflux permease	394
638192054	242	43.06	24	239	1	206	1.0e-42	167	COG1681	Archaeal flagellins	209
638192056	163	45.45	1	163	1	164	1.0e-47	182	COG2266	GTP:adenosylcobinamide-phosphate guanylyltransferase	177
638192057	247	38.37	1	247	2	258	6.0e-68	250	COG1120	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components	258
638192058	153	35.04	1	134	2	137	3.0e-27	114	COG1765	Predicted redox protein, regulator of disulfide bond formation	137
638192059	164	32.05	7	162	1	148	2.0e-20	92.4	COG2427	Uncharacterized conserved protein	148
638192060	381	20.95	8	365	1	361	3.0e-37	149	COG0446	Uncharacterized NAD(FAD)-dependent dehydrogenases	415
638192061	78	45.33	5	78	4	78	2.0e-15	73.8	COG0425	Predicted redox protein, regulator of disulfide bond formation	78
638192062	137	47.83	1	137	1	137	2.0e-36	144	COG2210	Uncharacterized conserved protein	137
638192063	113	44	7	105	1	99	1.0e-19	88.1	COG1761	DNA-directed RNA polymerase, subunit L	99
638192064	320	37.35	1	318	24	347	5.0e-89	321	COG1041	Predicted DNA modification methylase	347
638192065	604	32.92	1	530	1	564	6.0e-123	434	COG1293	Predicted RNA-binding protein homologous to eukaryotic snRNP	564
638192066	304	19.65	1	303	55	400	2.0e-46	180	COG0166	Glucose-6-phosphate isomerase	446
638192067	253	53.46	1	253	1	259	1.0e-93	336	COG3885	Uncharacterized conserved protein	261
638192069	153	45.22	1	152	3	159	5.0e-41	160	COG2016	Predicted RNA-binding protein (contains PUA domain)	161
638192071	288	26.4	132	288	1	178	1.0e-23	103	COG0250	Transcription antiterminator	178
638192072	104	36.49	31	104	1	65	1.0e-13	67.9	COG2443	Preprotein translocase subunit Sss1	65
638192074	376	72.65	2	373	1	369	0.0e+00	645	COG1980	Archaeal fructose 1,6-bisphosphatase	369
638192076	515	27.86	1	315	1	273	1.0e-45	177	COG1351	Predicted alternative thymidylate synthase	273
638192078	378	44.56	1	375	1	364	3.0e-104	372	COG2237	Predicted membrane protein	364
638192079	219	44.35	1	214	1	229	3.0e-68	251	COG1634	Uncharacterized Rossmann fold enzyme	232
638192080	221	38.97	4	212	4	216	2.0e-51	195	COG0235	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	219
638192082	118	58.82	1	118	1	117	6.0e-37	146	COG3462	Predicted membrane protein	117
638192084	314	39.68	3	312	4	309	4.0e-66	245	COG0650	Formate hydrogenlyase subunit 4	309
638192085	217	44.39	2	217	2	218	6.0e-52	197	COG4237	Hydrogenase 4 membrane component (E)	218
638192086	447	27.19	1	441	9	471	4.0e-48	185	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
638192087	389	38.11	38	389	1	370	5.0e-112	398	COG3261	Ni,Fe-hydrogenase III large subunit	382
638192088	222	47.59	84	222	4	148	1.0e-52	199	COG3260	Ni,Fe-hydrogenase III small subunit	148
638192089	589	24.49	40	454	71	492	8.0e-33	135	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
638192091	311	29.75	1	311	1	326	2.0e-42	166	COG0306	Phosphate/sulphate permeases	326
638192096	843	18.41	110	480	59	381	7.0e-13	69.7	COG1061	DNA or RNA helicases of superfamily II	442
638192097	616	14.08	6	614	1	578	3.0e-63	236	COG2189	Adenine specific DNA methylase Mod	590
638192098	129	18.27	26	129	194	292	1.0e-06	45.7	COG3385	FOG: Transposase and inactivated derivatives	292
638192100	297	22.91	13	265	57	331	4.0e-33	135	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
638192103	61	37.5	1	56	322	375	1.0e-06	44.6	COG3328	Transposase and inactivated derivatives	379
638192110	974	21.25	275	543	130	376	2.0e-13	72.1	COG1061	DNA or RNA helicases of superfamily II	442
638192111	681	13.31	47	668	1	590	4.0e-68	253	COG2189	Adenine specific DNA methylase Mod	590
638192112	373	23.12	36	371	4	362	8.0e-44	171	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
638192113	201	35.96	4	201	3	202	2.0e-32	132	COG1961	Site-specific recombinases, DNA invertase Pin homologs	222
638192117	251	41.63	1	251	3	258	1.0e-56	213	COG1192	ATPases involved in chromosome partitioning	259
638192127	429	24.25	19	280	17	256	6.0e-06	45.6	COG4974	Site-specific recombinase XerD	300
638192129	513	47.78	4	513	13	530	0.0e+00	643	COG1111	ERCC4-like helicases	542
638192130	330	30.63	27	330	1	321	2.0e-45	176	COG0470	ATPase involved in DNA replication	324
638192131	462	46.52	23	459	3	441	0.0e+00	519	COG0174	Glutamine synthetase	443
638192132	155	30.43	21	126	9	123	5.0e-14	70.6	COG1695	Predicted transcriptional regulators	138
638192133	1459	27.47	17	1458	1	1174	0.0e+00	634	COG4934	Predicted protease	1174
638192134	374	29.62	3	373	5	396	3.0e-58	219	COG0644	Dehydrogenases (flavoproteins)	396
638192135	280	21.29	20	275	30	281	8.0e-06	44.5	COG5006	Predicted permease, DMT superfamily	292
638192136	632	53.21	474	628	1	155	1.0e-55	211	COG1370	Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit	155
638192136	632	32.27	1	339	1	372	5.0e-98	352	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
638192137	592	59.22	3	592	2	591	0.0e+00	950	COG1245	Predicted ATPase, RNase L inhibitor (RLI) homolog	591
